OncomiR or tumor suppressor? The duplicity of microRNAs in cancer
AA Svoronos, DM Engelman, FJ Slack - Cancer research, 2016 - AACR
MicroRNAs (miRNA) are short, noncoding RNAs whose dysregulation has been implicated
in most, if not all, cancers. They regulate gene expression by suppressing mRNA translation …
in most, if not all, cancers. They regulate gene expression by suppressing mRNA translation …
Circular RNA: a new star of noncoding RNAs
Circular RNAs (circRNAs) are a novel type of RNA that, unlike linear RNAs, form a
covalently closed continuous loop and are highly represented in the eukaryotic …
covalently closed continuous loop and are highly represented in the eukaryotic …
[HTML][HTML] Circular RNAs: biogenesis, function and role in human diseases
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
miRNAs orchestration of adrenocortical carcinoma-Particular emphasis on diagnosis, progression and drug resistance
WA El-Dakroury, HM Midan, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Adrenocortical carcinoma (ACC) is an uncommon aggressive endocrine malignancy that is
nonetheless associated with significant mortality and morbidity rates because of endocrine …
nonetheless associated with significant mortality and morbidity rates because of endocrine …
microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance
MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
The emerging landscape of circular RNA in life processes
abstract Circular RNAs (circRNAs) are a novel class of non-coding RNA that assumes a
covalently closed continuous conformation. CircRNAs were previously thought to be the …
covalently closed continuous conformation. CircRNAs were previously thought to be the …
H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal …
E Zhang, L Han, D Yin, X He, L Hong, X Si… - Nucleic acids …, 2017 - academic.oup.com
Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …
[HTML][HTML] MiR-7-5p suppresses tumor metastasis of non-small cell lung cancer by targeting NOVA2
H Xiao - Cellular & Molecular Biology Letters, 2019 - Springer
Background Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality
worldwide. Distant metastasis is thought to be one of the most important factors responsible …
worldwide. Distant metastasis is thought to be one of the most important factors responsible …
[HTML][HTML] Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology
R Gambari, E Brognara… - … journal of oncology, 2016 - spandidos-publications.com
MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …
[HTML][HTML] MicroRNA as a potential therapeutic molecule in cancer
Small noncoding RNAs, as post-translational regulators of many target genes, are not only
markers of neoplastic disease initiation and progression, but also markers of response to …
markers of neoplastic disease initiation and progression, but also markers of response to …