Recent advances in exosome-mediated nucleic acid delivery for cancer therapy
Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …
challenge, although significant progress has been made in existing treatments in recent …
Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
Possibility of exosome-based therapeutics and challenges in production of exosomes eligible for therapeutic application
T Yamashita, Y Takahashi, Y Takakura - … and Pharmaceutical Bulletin, 2018 - jstage.jst.go.jp
Exosomes are cell-derived vesicles with a diameter 30–120 nm. Exosomes contain
endogenous proteins and nucleic acids; delivery of these molecules to exosome-recipient …
endogenous proteins and nucleic acids; delivery of these molecules to exosome-recipient …
Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …
Functional extracellular vesicles for regenerative medicine
The unique biological characteristics and promising clinical potential of extracellular
vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as …
vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as …
[HTML][HTML] Cellular and exosome mediated molecular defense mechanism in bovine granulosa cells exposed to oxidative stress
M Saeed-Zidane, L Linden, D Salilew-Wondim, E Held… - PloS one, 2017 - journals.plos.org
Various environmental insults including diseases, heat and oxidative stress could lead to
abnormal growth, functions and apoptosis in granulosa cells during ovarian follicle growth …
abnormal growth, functions and apoptosis in granulosa cells during ovarian follicle growth …
Extracellular vesicles in cancer diagnostics and therapeutics
Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …
[HTML][HTML] Exosomes–Spectacular role in reproduction
A Kowalczyk, M Wrzecińska… - Biomedicine & …, 2022 - Elsevier
Exosomes are nano-sized structures that are found in semen, epididymal–fluid,
endometrium, as well as in follicular fluid. They are responsible for transporting bioactive …
endometrium, as well as in follicular fluid. They are responsible for transporting bioactive …
The role of the metabolite cargo of extracellular vesicles in tumor progression
Metabolomic reprogramming in tumor and stroma cells is a hallmark of cancer but
understanding its effects on the metabolite composition and function of tumor-derived …
understanding its effects on the metabolite composition and function of tumor-derived …
Emerging function and clinical significance of exosomal circRNAs in cancer
M Wang, F Yu, P Li, K Wang - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Exosomes are a type of extracellular vesicles (EVs) secreted by almost all cells, with a
diameter range of 30–150 nm and a lipid bilayer membrane. Exosomes are now considered …
diameter range of 30–150 nm and a lipid bilayer membrane. Exosomes are now considered …