The ribosome-inactivating proteins (RIPs) from plants are RNA N-glycosidases that
depurinate the major rRNA, thus damaging ribosomes, and arresting protein synthesis [1-8] …

The main results of the research performed in the last 30 years on ribosome-inactivating
proteins (RIPs) are reviewed, with emphasis on the new, controversial and uncertain …

Ribosome-inactivating proteins (RIP) are a family of plant enzymes for which a unique
activity was determined: rRNA N-glycosidase at a specific universally conserved position, A …

Ribosome-Inactivating Proteins (RIPs) are enzymes that trigger the catalytic inactivation of
ribosomes and other substrates. They are present in a large number of plants and have …

Ribosome-inactivating proteins (RIPs) are toxins that act as N-glycosidases (EC 3.2. 2.22).
They are mainly produced by plants and classified as type 1 RIPs and type 2 RIPs. There …

Ribosome-inactivating proteins (RIPs) were first isolated over a century ago and have been
shown to be catalytic toxins that irreversibly inactivate protein synthesis. Elucidation of …

This review provides a historical overview of the research on plant ribosome-inactivating
proteins (RIPs), starting from the first studies at the end of eighteenth century involving the …

Thirty years ago, the type 1 ribosome-inactivating protein (RIP) saporin-S6 (also known as
saporin) was isolated from Saponaria officinalis L. seeds. Since then, the properties and …

Transition state theory teaches that chemically stable mimics of enzymatic transition states
will bind tightly to their cognate enzymes. Kinetic isotope effects combined with …

Ribosome‐inactivating proteins (RIPs) remove a specific adenine from 28S rRNA leading to
inactivation of ribosomes and arrest of translation. Great interest as to a possible second …