[HTML][HTML] Tissue fibroblasts are versatile immune regulators: an evaluation of their impact on the aging process

A Salminen, K Kaarniranta, A Kauppinen - Ageing Research Reviews, 2024 - Elsevier
Fibroblasts are abundant stromal cells which not only control the integrity of extracellular
matrix (ECM) but also act as immune regulators. It is known that the structural cells within …

Visualization Analysis of Small Extracellular Vesicles in the Application of Bone-Related Diseases

X Chen, N Yang, B Li, X Gao, Y Wang, Q Wang, X Liu… - Cells, 2024 - mdpi.com
Small extracellular vesicles were shown to have similar functional roles to their parent cells
without the defect of potential tumorigenicity, which made them a great candidate for …

Extracellular vesicles from senescent mesenchymal stromal cells are defective and cannot prevent osteoarthritis

J Boulestreau, M Maumus, GM Bertolino… - Journal of …, 2024 - Springer
Age is the most important risk factor in degenerative diseases such as osteoarthritis (OA),
which is associated with the accumulation of senescent cells in the joints. Here, we aimed to …

The Molecular Mechanisms in Senescent Cells Induced by Natural Aging and Ionizing Radiation

M Ibragimova, A Kussainova, A Aripova, R Bersimbaev… - Cells, 2024 - mdpi.com
This review discusses the relationship between cellular senescence and radiation exposure.
Given the wide range of ionizing radiation sources encountered by people in professional …

Multi-omic temporal landscape of plasma and synovial fluid-derived extracellular vesicles using an experimental model of equine osteoarthritis

JR Anderson, E Johnson, R Jenkins… - International journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) contribute to osteoarthritis pathogenesis through their release
into joint tissues and synovial fluid. Synovial fluid-derived EVs have the potential to be direct …

Le profil sécrétoire des macrophages sénescents est composé de vésicules extracellulaires enrichies en oncomiR

B Bossé - 2024 - papyrus.bib.umontreal.ca
Le vieillissement est l'un premier facteur de risque pour plusieurs maladies telles que
l'athérosclérose, la fibrose, l'Alzheimer, le diabète de type 2 et le cancer. L'accumulation de …