LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway

C Wei, X Dong, H Lu, F Tong, L Chen, R Zhang… - Journal of Experimental …, 2019 - Springer
Background Brain metastasis (BM) is associated with poor prognosis, recurrence, and death
in patients with non-small cell lung cancer (NSCLC). Lysophosphatidylcholine …

Novel gene signatures for prognosis prediction in ovarian cancer

M Bao, L Zhang, Y Hu - Journal of Cellular and Molecular …, 2020 - Wiley Online Library
Ovarian cancer (OV) is one of the leading causes of cancer deaths in women worldwide.
Late diagnosis and heterogeneous treatment result to poor survival outcomes for patients …

Switching mechanism from AR to EGFR signaling via 3-O-sulfated heparan sulfate in castration-resistant prostate cancer

H Ota, H Sato, S Mizumoto, K Wakai, K Yoneda… - Scientific Reports, 2023 - nature.com
Androgen deprivation therapy is given to suppress prostate cancer growth; however, some
cells continue to grow hormone-independently as castration-resistant prostate cancer …

miR-138-5p inhibits the malignant progression of prostate cancer by targeting FOXC1

D Zhang, X Liu, Q Zhang, X Chen - Cancer cell international, 2020 - Springer
Background This study aimed to uncover the effect of miR-138-5p on the proliferation and
metastasis of PCa cell lines, and further explore the potential regulatory mechanisms via …

Docetaxel resistance in castration-resistant prostate cancer: transcriptomic determinants and the effect of inhibiting Wnt/β-catenin signaling by XAV939

E Pudova, A Kobelyatskaya, I Katunina… - International Journal of …, 2022 - mdpi.com
Castration-resistant prostate cancer (CRPC) is a common form of prostate cancer in which
docetaxel-based chemotherapy is used as the first line. The present study is devoted to the …

Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells

YL Chen, YC Yen, CW Jang, SH Wang, HT Huang… - Scientific reports, 2021 - nature.com
Ephrin type-A receptor 10 (EPHA10) has been implicated as a potential target for breast and
prostate cancer therapy. However, its involvement in oral squamous cell carcinoma (OSCC) …

Identification and characterization of key differentially expressed genes associated with metronomic dosing of topotecan in human prostate cancer

T Mitra Ghosh, J White, J Davis, S Mazumder… - Frontiers in …, 2021 - frontiersin.org
Repetitive, low-dose (metronomic; METRO) drug administration of some anticancer agents
can overcome drug resistance and increase drug efficacy in many cancers, but the …

Whole-genome sequencing of prostate cancer reveals novel mutation-driven processes and molecular subgroups

C Liang, L Niu, Z Xiao, C Zheng, Y Shen, Y Shi, X Han - Life sciences, 2020 - Elsevier
Prostate cancer (PCa) is the second most frequently diagnosed cancer in men. However, its
genetic characteristics in the Chinese population have not been extensively profiled. Here …

Expression pattern of genes associated with tumor microenvironment in prostate cancer

GV Gerashchenko, OV Grygoruk… - Experimental …, 2018 - exp-oncology.com.ua
Aim: To assess relative expression (RE) levels of CAF-, TAM-specific, immune defense-
associated genes in prostate tumors and to show correlation of RE with clinical, pathological …

17 variants interaction of Wnt/β-catenin pathway associated with development of osteonecrosis of femoral head in Chinese Han population

C Shi, X Li, Y Sun, Z Du, G Zhang, Z Che, Q Li… - Scientific Reports, 2024 - nature.com
The genes of Wnt/β-catenin pathway may have potential roles in fat accumulation of Non-
traumatic osteonecrosis of the femoral head (ONFH), but the effects of their variants in the …