Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with
intrinsic abilities to identify and eliminate virally infected cells and tumour cells. Possessing …

Killer immunoglobulin-like receptors (KIR) regulate the function of natural killer cells through
interactions with various ligands on the surface of cells, thereby determining whether natural …

Natural killer (NK) cells derived or isolated from different sources have been gaining in
importance for cancer therapies. In this study, we evaluate and compare key characteristics …

Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …

Optimizing natural killer (NK) cell alloreactivity could further improve outcome after
allogeneic hematopoietic cell transplantation (alloHCT). The donor's Killer-cell …

With the continuous increase in the use of haploidentical donors for transplantation, the
selection of donors becomes increasingly important. Haploidentical donors have been …

In acute myeloid leukemia (AML), donor natural killer cell killer immunoglobulin–like
receptors (KIR) and recipient HLA interactions may contribute to the graft-versus-leukemia …

Due to their intrinsic ability to eliminate malignant cells, natural killer (NK) cells emerge as a
promising immunotherapy for cancer. While clinical studies have affirmed the safety of NK …

Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity
mediated through Killer cell Immunoglobulin-like Receptors (KIR) could reduce the risk of …

Natural killer (NK) cells are an important defender against infections and tumors. Their
function is regulated by the balance of inhibitory and activating receptors. Among all …