As photodynamic therapy (PDT) becomes established as a treatment for cancer, there is
increasing interest in identifying critical mechanisms of cell killing and understanding the …

Photodynamic therapy (PDT) is a two‐step therapeutic technique in which the topical or
systemic delivery of photosensitizing drugs is followed by irradiation with visible light …

The introduction of lipophilic derivatives of the naturally occurring heme precursor 5‐
aminolevulinic acid (5‐ALA) into photomedicine has led to a true revival of this research …

Photodynamic therapy (PDT) is a tool for the treatment of certain cancerous and pre-
cancerous conditions in dermatology. 5-Aminolevulinic acid (5-ALA) and simple derivatives …

The number of non-melanoma skin cancers is increasing worldwide, and so also the
demand for effective treatment modalities. Topical photodynamic therapy (PDT) using …

Due to its capability to induce accumulation of protoporphyrin IX (PpIX) selectively in a
multitude of different pathologies, 5-aminolevulinic acid (ALA) and its derivatives have …

Abstract δ‐Aminolevulinic acid (ALA)‐induced protoporphyrin accumulation is widely used
in the treatment of cancer, as photodynamic therapy (PDT). To clarify the mechanisms of …

Photodynamic therapy requires a photosensitizer, oxygen, and activating light. For acne,
pilosebaceous units are “target” structures. Porphyrins are synthesized in vivo from 5 …

Background Topical photodynamic therapy (PDT) is widely used to treat superficial
nonmelanoma skin cancer and dysplasia, and is generally well tolerated. However, as with …

Aminolevulinic acid (ALA)–induced protoporphyrin IX (PPIX) fluorescence has been shown
to have high tumor cell selectivity in various organs, including the gastrointestinal (GI) tract …