Although liver transplantation is a true success story, many patients still die awaiting an
organ. The increasing need for liver grafts therefore remains an unsolved challenge to the …

A short period (1–2 h) of hypothermic oxygenated machine perfusion (HOPE) after static
cold storage is safe and reduces ischemia‐reperfusion injury‐related complications after …

The widespread uptake of different machine perfusion (MP) strategies for liver transplant has
been driven by an effort to minimize graft injury. Damage to the cholangiocytes during the …

Partial liver grafts from ex situ splitting are considered marginal due to prolonged static cold
storage. The use of ex situ hypothermic oxygenated perfusion (HOPE) may offer a strategy to …

Machine perfusion has developed rapidly since its first use in solid organ transplantation.
Likewise, reconstructive surgery has kept pace, and ex vivo perfusion appears as a new …

Abstract Hypothermic Oxygenated machine PErfusion (HOPE) has recently emerged as a
preservation technique which can reduce ischemic injury and improve clinical outcomes …

Since the advent of University of Wisconsin preservation solution in the 1980s clinicians
have learned to work within its confines. While affording improved outcomes, considerable …

The acceptance of liver transplantation as the standard of care for end-stage liver diseases
has led to a critical shortage of donor allografts. To expand the donor organ pool, many …

Background Ex vivo split liver transplantation in pediatric recipients has shown inferior
results compared with whole grafts. One factor among others contributing to split grafts being …

Background. Hypothermic oxygenated perfusion (HOPE) improves outcomes of marginal
liver grafts. However, to date, no preservation solution exists for both static cold storage …