Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children
AW Kay, LG Fernández, Y Takwoingi… - Cochrane Database …, 2020 - cochranelibrary.com
Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …
Diagnostic accuracy of stool Xpert MTB/RIF for detection of pulmonary tuberculosis in children: a systematic review and meta-analysis
Invasive collection methods are often required to obtain samples for the microbiological
evaluation of children with presumptive pulmonary tuberculosis (PTB). Nucleic acid …
evaluation of children with presumptive pulmonary tuberculosis (PTB). Nucleic acid …
[图书][B] WHO consolidated guidelines on tuberculosis. Module 5: management of tuberculosis in children and adolescents
World Health Organization - 2022 - books.google.com
The objectives of the 2022 consolidated guidelines are: to provide policy makers and
implementing partners with evidence-based recommendations on the cascade of care for …
implementing partners with evidence-based recommendations on the cascade of care for …
Host-response-based gene signatures for tuberculosis diagnosis: A systematic comparison of 16 signatures
Background The World Health Organization (WHO) and Foundation for Innovative New
Diagnostics (FIND) have published target product profiles (TPPs) calling for non-sputum …
Diagnostics (FIND) have published target product profiles (TPPs) calling for non-sputum …
Challenges and controversies in childhood tuberculosis
A Reuter, J Hughes, J Furin - The Lancet, 2019 - thelancet.com
Children bear a substantial burden of suffering when it comes to tuberculosis. Ironically, they
are often left out of the scientific and public health advances that have led to important …
are often left out of the scientific and public health advances that have led to important …
Sensitive and feasible specimen collection and testing strategies for diagnosing tuberculosis in young children
R Song, ES Click, KD McCarthy, CM Heilig… - JAMA …, 2021 - jamanetwork.com
Importance Criterion-standard specimens for tuberculosis diagnosis in young children,
gastric aspirate (GA) and induced sputum, are invasive and rarely collected in resource …
gastric aspirate (GA) and induced sputum, are invasive and rarely collected in resource …
Diagnostic advances in childhood tuberculosis—improving specimen collection and yield of microbiological diagnosis for intrathoracic tuberculosis
E Wobudeya, M Bonnet, EG Walters, P Nabeta, R Song… - Pathogens, 2022 - mdpi.com
There is no microbiological gold standard for childhood tuberculosis (TB) diagnosis. The
paucibacillary nature of the disease, challenges in sample collection in young children, and …
paucibacillary nature of the disease, challenges in sample collection in young children, and …
Stool Xpert MTB/RIF and urine lipoarabinomannan for the diagnosis of tuberculosis in hospitalized HIV-infected children
Background: Tuberculosis (TB) causes substantial morbidity and mortality in HIV-infected
children. Sample collection and the paucibacillary nature of TB in children makes diagnosis …
children. Sample collection and the paucibacillary nature of TB in children makes diagnosis …
Development of a treatment-decision algorithm for human immunodeficiency virus–uninfected children evaluated for pulmonary tuberculosis
KS Gunasekera, E Walters… - Clinical Infectious …, 2021 - academic.oup.com
Background Limitations in the sensitivity and accessibility of diagnostic tools for childhood
tuberculosis contribute to the substantial gap between estimated cases and cases notified to …
tuberculosis contribute to the substantial gap between estimated cases and cases notified to …
Xpert Ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis
N Mafirakureva, E Klinkenberg, I Spruijt, J Levy… - BMJ open, 2022 - bmjopen.bmj.com
Objectives The WHO currently recommends stool testing using GeneXpert MTB/Rif (Xpert)
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …