A delicate balance: Iron metabolism and diseases of the brain

D Hare, S Ayton, A Bush, P Lei - Frontiers in aging neuroscience, 2013 - frontiersin.org
Iron is the most abundant transition metal within the brain, and is vital for a number of
cellular processes including neurotransmitter synthesis, myelination of neurons, and …

Magnetic resonance imaging quantification of liver iron

CB Sirlin, SB Reeder - Magnetic Resonance Imaging Clinics, 2010 - mri.theclinics.com
Hepatic iron overload is the abnormal and excessive intracellular accumulation of iron in
hepatocytes, Kupffer cells, or both hepatocytes and Kupffer cells, primarily as ferritin …

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells

DB Kell, E Pretorius - Metallomics, 2014 - academic.oup.com
Abstract" Serum ferritin" presents a paradox, as the iron storage protein ferritin is not
synthesised in serum yet is to be found there. Serum ferritin is also a well known …

Hepatic MR elastography: clinical performance in a series of 1377 consecutive examinations

M Yin, KJ Glaser, JA Talwalkar, J Chen, A Manduca… - Radiology, 2016 - pubs.rsna.org
Purpose To assess the technical success rate and diagnostic performance of liver magnetic
resonance (MR) elastography. Materials and Methods This retrospective study was …

Practical guide to quantification of hepatic iron with MRI

B Henninger, J Alustiza, M Garbowski, Y Gandon - European radiology, 2020 - Springer
Our intention is to demystify the MR quantification of hepatic iron (ie, the liver iron
concentration) and give you a step-by-step approach by answering the most pertinent …

Technical failure of MR elastography examinations of the liver: experience from a large single-center study

M Wagner, I Corcuera-Solano, G Lo, S Esses, J Liao… - Radiology, 2017 - pubs.rsna.org
Purpose To assess the determinants of technical failure of magnetic resonance (MR)
elastography of the liver in a large single-center study. Materials and Methods This …

Combination of complex‐based and magnitude‐based multiecho water‐fat separation for accurate quantification of fat‐fraction

H Yu, A Shimakawa, CDG Hines… - Magnetic resonance …, 2011 - Wiley Online Library
Multipoint water–fat separation techniques rely on different water–fat phase shifts generated
at multiple echo times to decompose water and fat. Therefore, these methods require …

Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM

MS Petronek, V Monga, KL Bodeker, M Kwofie… - Clinical Cancer …, 2024 - AACR
Abstract Purpose: Pharmacologic ascorbate (P-AscH−) is hypothesized to be an iron (Fe)-
dependent tumor-specific adjuvant to chemoradiation in treating glioblastoma (GBM). This …

The close link of pancreatic iron with glucose metabolism and with cardiac complications in thalassemia major: a large, multicenter observational study

A Pepe, L Pistoia, MR Gamberini, L Cuccia… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE We systematically explored the link of pancreatic iron with glucose metabolism
and with cardiac complications in a cohort of 1,079 patients with thalassemia major (TM) …

Prediction of cardiac complications for thalassemia major in the widespread cardiac magnetic resonance era: a prospective multicentre study by a multi-parametric …

A Pepe, A Meloni, G Rossi, M Midiri… - European Heart …, 2018 - academic.oup.com
Aims Cardiovascular magnetic resonance (CMR) has dramatically changed the clinical
practice in thalassemia major (TM), lowering cardiac complications. We prospectively …