Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This
paper reviews the general management and standard radiotherapy guidelines for …

Osteosarcoma is the bone tumor that most commonly affects children, adolescents, and
young adults. Before 1970, treatment primarily included surgical resection. However, the …

Highlights•This Clinical Practice Guideline provides key recommendations on the
management of bone sarcomas.•Recommendations have been agreed following a …

Primary bone tumours are rare, accounting for< 0.2% of malignant neoplasms registered in
the EUROCARE (European Cancer Registry based study on survival and care of cancer …

Osteosarcoma is the most common primary malignant bone tumour in children and
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …

Osteosarcoma (OS), chondrosarcoma, and chordoma are characterized by multiple
challenges to the investigator, clinician, and patient. One consequence of their rarity among …

Background We designed the EURAMOS-1 trial to investigate whether intensified
postoperative chemotherapy for patients whose tumour showed a poor response to …

Clinical outcomes and treatment modalities for osteosarcoma, the most common primary
cancer of bone, have changed very little over the past 30 years. The peak incidence of …

Survival in osteosarcoma is a story of success on many fronts. What was once a disease that
was rarely curable even with ablative surgery now has a 5-year overall survival approaching …

Osteosarcoma is the most common primary malignancy of bone in children and young
adults. This tumor has a very heterogeneous genetic profile and lacks any consistent …