Novel insights into the interplay between m6A modification and noncoding RNAs in cancer
YC Yi, XY Chen, J Zhang, JS Zhu - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …
Expanded encyclopaedias of DNA elements in the human and mouse genomes
The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate …
govern the timing, magnitude, and cellular context of their production. To better delineate …
The ENCODE uniform analysis pipelines
The Encyclopedia of DNA elements (ENCODE) project is a collaborative effort to create a
comprehensive catalog of functional elements in the human genome. The current database …
comprehensive catalog of functional elements in the human genome. The current database …
[HTML][HTML] The changing mouse embryo transcriptome at whole tissue and single-cell resolution
P He, BA Williams, D Trout, GK Marinov, H Amrhein… - Nature, 2020 - nature.com
During mammalian embryogenesis, differential gene expression gradually builds the identity
and complexity of each tissue and organ system. Here we systematically quantified mouse …
and complexity of each tissue and organ system. Here we systematically quantified mouse …
The lncRNA XIST/miR-150-5p/c-Fos axis regulates sepsis-induced myocardial injury via TXNIP-modulated pyroptosis
X Wang, XL Li, LJ Qin - Laboratory Investigation, 2021 - nature.com
Myocardial injury is a severe complication of sepsis and contributes substantially to the
death of critically ill patients. Long non-coding RNAs (lncRNAs) participate in the …
death of critically ill patients. Long non-coding RNAs (lncRNAs) participate in the …
Cystoid macular oedema following Descemet membrane endothelial keratoplasty
S Heinzelmann, P Maier, D Böhringer… - British Journal of …, 2015 - bjo.bmj.com
Background To determine the incidence and potential risk factors of cystoid macular
oedema (CMO) following Descemet membrane endothelial keratoplasty (DMEK) with or …
oedema (CMO) following Descemet membrane endothelial keratoplasty (DMEK) with or …
Canalization of phenotypes—when the transcriptome is constantly but weakly perturbed
Recent studies have increasingly pointed to microRNAs (miRNAs) as the agent of gene
regulatory network (GRN) stabilization as well as developmental canalization against …
regulatory network (GRN) stabilization as well as developmental canalization against …
Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model
Background MicroRNAs (miRNAs) are important post-transcriptional gene regulators
controlling cellular lineage specification and differentiation during embryonic development …
controlling cellular lineage specification and differentiation during embryonic development …
The embryonic transcriptome of Parhyale hawaiensis reveals different dynamics of microRNAs and mRNAs during the maternal-zygotic transition
L Calvo, M Birgaoanu, T Pettini, M Ronshaugen… - Scientific Reports, 2022 - nature.com
Parhyale hawaiensis has emerged as the crustacean model of choice due to its tractability,
ease of imaging, sequenced genome, and development of CRISPR/Cas9 genome editing …
ease of imaging, sequenced genome, and development of CRISPR/Cas9 genome editing …
Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals
Canonical microRNA (miRNA) hairpins are processed by the RNase III enzymes Drosha
and Dicer into∼ 22 nt RNAs loaded into an Argonaute (Ago) effector. In addition, splicing …
and Dicer into∼ 22 nt RNAs loaded into an Argonaute (Ago) effector. In addition, splicing …