Xenotransplantation may be a solution to overcome the shortage of organs for the treatment
of patients with organ failure, but it may be associated with the transmission of porcine …

Background The pig‐to‐non‐human primate model is the standard choice for in vivo studies
of organ and cell xenotransplantation. In 1998, Lambrigts and his colleagues surveyed the …

Porcine kidney xenotransplantation is accelerating towards clinical translation. However,
despite the demonstrated ability of porcine kidneys to remove metabolic waste products …

Background. Thechronic shortage in the supply of human organs available for
allotransplantation has turned attention toward the use of animals as potential donors, with …

Farm animals and their products have a longstanding and successful history of providing
significant contributions to human nutrition, clothing, facilitation of labour, research …

An urgent and steadily increasing need exists worldwide for a greater supply of donor
thoracic organs. Xenotransplantation offers the possibility of an unlimited supply of hearts …

Background. In pig-to-primate organ transplantation, hyperacute rejection can be prevented,
but the organ is rejected within days by acute vascular rejection, in which induced high …

Background. The genetic modification of pigs is a powerful strategy that may ultimately
enable successful xenotransplantation of porcine organs into humans. Methods. Transgenic …

Background. Recently, there has been a resumed interest in clinical xenotransplantation
using pig organs. However, no data are available yet regarding the capacity of porcine …

Xenotransplantation using pig organs could solve the significant increasing shortage of
donor organs for allotransplantation. In the last two decades, major progress has been made …