Oxidative DNA damage in the pathophysiology of spinal cord injury: seems obvious, but where is the evidence?

EEM Scheijen, S Hendrix, DM Wilson III - Antioxidants, 2022 - mdpi.com
Oxidative stress occurs at various phases of spinal cord injury (SCI), promoting detrimental
processes such as free radical injury of proteins, nucleic acids, lipids, cytoskeleton, and …

Blast-overpressure induced modulation of PARP-SIRT-NRF2 axis in stress signaling of astrocytes and microglia.

VPK MUTHAIAH, K Kaliyappan, S Mahajan… - Authorea …, 2024 - authorea.com
Background: The pathomechanism of blast TBI and blunt TBI is different. In blast injury,
evidence indicate that a single blast exposure can often manifest long-term neurological …