The endocannabinoid system: a potential target for the treatment of various diseases
H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …
balance in internal environment (temperature, mood, and immune system) and energy input …
A comparative overview on chili pepper (capsicum genus) and sichuan pepper (zanthoxylum genus): From pungent spices to pharma-foods
D Zhang, X Sun, M Battino, X Wei, J Shi, L Zhao… - Trends in Food Science …, 2021 - Elsevier
Abstract Background Both Chili pepper (CP) and Sichuan pepper (SP) have long been used
for culinary purposes throughout Asia. It is well known CP and SP are well accompanied in …
for culinary purposes throughout Asia. It is well known CP and SP are well accompanied in …
Possible use of phytochemicals for recovery from COVID-19-induced anosmia and ageusia
The year 2020 became the year of the outbreak of coronavirus, SARS-CoV-2, which
escalated into a worldwide pandemic and continued into 2021. One of the unique symptoms …
escalated into a worldwide pandemic and continued into 2021. One of the unique symptoms …
A systematic review of the biological mediators of fat taste and smell
RB Jaime-Lara, BE Brooks, C Vizioli… - Physiological …, 2023 - journals.physiology.org
Taste and smell play a key role in our ability to perceive foods. Overconsumption of highly
palatable energy-dense foods can lead to increased caloric intake and obesity. Thus there is …
palatable energy-dense foods can lead to increased caloric intake and obesity. Thus there is …
Mechanosensitive TRPV4 is required for crystal-induced inflammation
Crystal structures activate innate immune cells, especially macrophages and initiate
inflammatory responses. We aimed to understand the role of the mechanosensitive TRPV4 …
inflammatory responses. We aimed to understand the role of the mechanosensitive TRPV4 …
A review on the role of TRP channels and their potential as drug targets_an insight into the TRP channel drug discovery methodologies
HP Fallah, E Ahuja, H Lin, J Qi, Q He, S Gao… - Frontiers in …, 2022 - frontiersin.org
Transient receptor potential (TRP) proteins are a large group of ion channels that control
many physiological functions in our body. These channels are considered potential …
many physiological functions in our body. These channels are considered potential …
TRPM channels in human diseases
The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
Preparation, pungency and bioactivity of gingerols from ginger (Zingiber officinale Roscoe): a review
Y Gao, Y Lu, N Zhang, CC Udenigwe… - Critical Reviews in …, 2024 - Taylor & Francis
Ginger has been widely used for different purposes, such as condiment, functional food,
drugs, and cosmetics. Gingerols, the main pungent component in ginger, possess a variety …
drugs, and cosmetics. Gingerols, the main pungent component in ginger, possess a variety …
Interactions between chemesthesis and taste: role of TRPA1 and TRPV1
MR Rhyu, Y Kim, V Lyall - International journal of molecular sciences, 2021 - mdpi.com
In addition to the sense of taste and olfaction, chemesthesis, the sensation of irritation,
pungency, cooling, warmth, or burning elicited by spices and herbs, plays a central role in …
pungency, cooling, warmth, or burning elicited by spices and herbs, plays a central role in …
Taste and smell: a unifying chemosensory theory
Since antiquity, the sense of smell (olfaction) is considered as a distance sense, just like
sight and hearing. Conversely, the sense of taste (gustation) is thought to operate by direct …
sight and hearing. Conversely, the sense of taste (gustation) is thought to operate by direct …