Cell‐based delivery systems: emerging carriers for immunotherapy

Z Li, Y Wang, Y Ding, L Repp… - Advanced Functional …, 2021 - Wiley Online Library
Immunotherapy is leading a paradigm shift in the treatment of various diseases, including
tumors, auto‐immune diseases, and infectious diseases. However, the limited response rate …

Stem cell-based therapies for cancer treatment: separating hope from hype

DW Stuckey, K Shah - Nature Reviews Cancer, 2014 - nature.com
Stem cell-based therapies are emerging as a promising strategy to tackle cancer. Multiple
stem cell types have been shown to exhibit inherent tropism towards tumours. Moreover …

[HTML][HTML] Stem cell membrane-camouflaged targeted delivery system in tumor

W Zhang, X Huang - Materials Today Bio, 2022 - Elsevier
Cell membrane-coated nanoparticles (NPs) have attracted growing attention in the field of
targeted delivery strategies, which successfully combine the advantages and properties of …

Generation of “off-the-shelf” natural killer cells from peripheral blood cell-derived induced pluripotent stem cells

J Zeng, SY Tang, LL Toh, S Wang - Stem cell reports, 2017 - cell.com
Current donor cell-dependent strategies can only produce limited" made-to-order"
therapeutic natural killer (NK) cells for limited patients. To provide unlimited" off-the-shelf" …

Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis

J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang… - Cell research, 2020 - nature.com
Lung injury and fibrosis represent the most significant outcomes of severe and acute lung
disorders, including COVID-19. However, there are still no effective drugs to treat lung injury …

Selective ablation of tumorigenic cells following human induced pluripotent stem cell-derived neural stem/progenitor cell transplantation in spinal cord injury

K Kojima, H Miyoshi, N Nagoshi… - Stem Cells …, 2019 - academic.oup.com
Tumorigenesis is an important problem that needs to be addressed in the field of human
stem/progenitor cell transplantation for the treatment of subacute spinal cord injury (SCI) …

Tumor-homing cytotoxic human induced neural stem cells for cancer therapy

JR Bagó, O Okolie, R Dumitru, MG Ewend… - Science translational …, 2017 - science.org
Engineered neural stem cells (NSCs) are a promising approach to treating glioblastoma
(GBM). The ideal NSC drug carrier for clinical use should be easily isolated and autologous …

A nanotherapeutic system for gastric cancer suppression by synergistic chemotherapy and immunotherapy based on iPSCs and DCs exosomes

Y Li, L Tian, T Zhao, J Zhang - Cancer Immunology, Immunotherapy, 2023 - Springer
Background Chemotherapeutic drugs, the indispensable therapy in the treatment of gastric
cancer, contain many problems such as high organ toxicity and insufficient therapeutic …

Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications

W Zhang, X Huang - Inflammation and Regeneration, 2023 - Springer
Stem cell-based therapy is widely accepted to be a promising strategy in tissue regenerative
medicine. Nevertheless, there are several obstacles to applying stem cells in skin …

Concise review: neural stem cell-mediated targeted cancer therapies

R Mooney, M Hammad, J Batalla-Covello… - Stem Cells …, 2018 - academic.oup.com
Cancer is one of the leading causes of morbidity and mortality worldwide, with 1,688,780
new cancer cases and 600,920 cancer deaths projected to occur in 2017 in the US alone …