Advances in the management of peritoneal malignancies

V Kepenekian, A Bhatt, J Peron, M Alyami… - Nature Reviews …, 2022 - nature.com
Peritoneal surface malignancies (PSMs) are usually associated with a poor prognosis.
Nonetheless, in line with advances in the management of most abdominopelvic metastatic …

New developments in mesothelial pathology

A Churg - Histopathology, 2024 - Wiley Online Library
This review article examines some new and some problem areas in mesothelial pathology,
four of which are discussed, as follows.(1) The concept of mesothelioma in situ: this lesion is …

Intracranial mesenchymal tumor with FET‐CREB fusion—a unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous …

EA Sloan, J Chiang, JE Villanueva‐Meyer… - Brain …, 2021 - Wiley Online Library
Intracranial mesenchymal tumors with FET‐CREB fusions are a recently described group of
neoplasms in children and young adults characterized by fusion of a FET family gene …

The spectrum of rare central nervous system (CNS) tumors with EWSR1‐non‐ETS fusions: experience from three pediatric institutions with review of the literature

O Lopez‐Nunez, B Cafferata, M Santi… - Brain …, 2021 - Wiley Online Library
The group of CNS mesenchymal (non‐meningothelial) and primary glial/neuronal tumors in
association with EWSR1‐non‐ETS rearrangements comprises a growing spectrum of …

[HTML][HTML] Comprehensive genomic profiling of EWSR1/FUS:: CREB translocation-associated tumors uncovers prognostically significant recurrent genetic alterations …

JK Dermawan, F Vanoli, L Herviou, YS Sung, L Zhang… - Modern Pathology, 2022 - Elsevier
To elucidate the mechanisms underlying the divergent clinicopathologic spectrum of
EWSR1/FUS:: CREB translocation-associated tumors, we performed a comprehensive …

EWSR1—The Most Common Rearranged Gene in Soft Tissue Lesions, Which Also Occurs in Different Bone Lesions: An Updated Review

U Flucke, MM van Noesel, V Siozopoulou, D Creytens… - Diagnostics, 2021 - mdpi.com
EWSR1 belongs to the FET family of RNA-binding proteins including also Fused in Sarcoma
(FUS), and TATA-box binding protein Associated Factor 15 (TAF15). As consequence of the …

Guidelines for pathologic diagnosis of mesothelioma: 2023 update of the consensus statement from the international mesothelioma interest group

AN Husain, DB Chapel, R Attanoos… - … of Pathology & …, 2024 - meridian.allenpress.com
Context.—Mesothelioma is an uncommon tumor that can be difficult to diagnose. Objective.—
To provide updated, practical guidelines for the pathologic diagnosis of mesothelioma. Data …

The cAMP-signaling cancers: Clinically-divergent disorders with a common central pathway

GB Bolger - Frontiers in Endocrinology, 2022 - frontiersin.org
The cAMP-signaling cancers, which are defined by functionally-significant somatic mutations
in one or more elements of the cAMP signaling pathway, have an unexpectedly wide range …

POU2AF3‐rearranged sarcomas: A novel tumor defined by fusions of EWSR1 or FUS to a gene formerly designated COLCA2

MC Hiemenz, J Kaur, Z Kuang… - Genes …, 2023 - Wiley Online Library
Gene fusions involving EWSR1 or FUS as the 5′ partner have been reported in a diverse
array of sarcomas. Here, we characterize the histopathology and genomics of six tumors …

Cytokeratin-positive malignant tumor in the abdomen with EWSR1/FUS-CREB fusion: a clinicopathologic study of 8 cases

T Shibayama, T Shimoi, T Mori, E Noguchi… - The American journal …, 2022 - journals.lww.com
Abstract ATF1, CREB1, and CREM, which encode the CREB family of transcription factors,
are fused with EWSR1 or FUS in human neoplasms, such as angiomatoid fibrous …