[HTML][HTML] The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility

JR Kovac, AW Pastuszak, DJ Lamb - Fertility and sterility, 2013 - Elsevier
Although male factors account for approximately 50% of all infertility, the mechanisms
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …

A systems view of the heparan sulfate interactome

A Gómez Toledo, JT Sorrentino… - … of Histochemistry & …, 2021 - journals.sagepub.com
Heparan sulfate proteoglycans consist of a small family of proteins decorated with one or
more covalently attached heparan sulfate glycosaminoglycan chains. These chains have …

Evolution and function of mammalian binder of sperm proteins

G Plante, B Prud'homme, J Fan, M Lafleur… - Cell and Tissue …, 2016 - Springer
Binder of sperm (BSP) proteins are ubiquitous among mammals and have been extensively
investigated over the last three decades. They were first characterized in bull seminal …

Seminal plasma components in camelids and comparisons with other species

CM Kershaw‐Young… - Reproduction in domestic …, 2012 - Wiley Online Library
Contents Camelid semen is characterized by a highly viscous, low‐volume ejaculate with a
low concentration of spermatozoa that exhibit low progressive motility. The viscous seminal …

Proteomics of human seminal plasma: identification of biomarker candidates for fertility and infertility and the evolution of technology

D Milardi, G Grande, F Vincenzoni… - Molecular …, 2013 - Wiley Online Library
Proteomics is a research area that has developed rapidly in the last decade. It studies the
large‐scale characterization of the full protein components of a cell, a tissue, or a biological …

New properties of a well-known antioxidant: pleiotropic effects of human lactoferrin in mice exposed to gamma irradiation in a sublethal dose

MY Kopaeva, IB Alchinova, AB Cherepov… - Antioxidants, 2022 - mdpi.com
We studied the effects of human lactoferrin (hLf), a multifunctional protein from the transferrin
family, on integral (survival, lifespan during the experiment, body weight, behavior …

Proteomic analysis of heparin-binding proteins from human seminal plasma: a step towards identification of molecular markers of male fertility

V Kumar, MI Hassan, AK Tomar, T Kashav… - Journal of …, 2009 - Springer
Glycosaminoglycans, especially heparin, are involved in various cell processes such as
apoptosis, cell cycle control, platelet activation, capacitation, acrosome reaction and sperm …

Hyphenated techniques for the analysis of heparin and heparan sulfate

B Yang, K Solakyildirim, Y Chang… - Analytical and bioanalytical …, 2011 - Springer
The elucidation of the structure of glycosaminoglycan has proven to be challenging for
analytical chemists. Molecules of glycosaminoglycan have a high negative charge and are …

Determination of testicular function in adolescents with varicocoele–a proteomics approach

PT Del Giudice, LB Belardin, M Camargo… - …, 2016 - Wiley Online Library
The goal of this study was to determine seminal plasma biomarkers of testicular function in
adolescents with varicocoele and to verify enriched gene ontology terms associated to these …

Pretreatment with human lactoferrin had a positive effect on the dynamics of mouse nigrostriatal system recovery after acute MPTP exposure

MY Kopaeva, AB Cherepov, MV Nesterenko… - Biology, 2021 - mdpi.com
Simple Summary Parkinson's disease (PD) is the progressive neurodegenerative disorder
characterized by the degeneration of dopaminergic neurons in substantia nigra and …