Taxonomic use of DNA G+ C content and DNA–DNA hybridization in the genomic age
JP Meier-Kolthoff, HP Klenk… - International journal of …, 2014 - microbiologyresearch.org
The G+ C content of a genome is frequently used in taxonomic descriptions of species and
genera. In the past it has been determined using conventional, indirect methods, but it is …
genera. In the past it has been determined using conventional, indirect methods, but it is …
A polyphasic strategy incorporating genomic data for the taxonomic description of novel bacterial species
Currently, bacterial taxonomy relies on a polyphasic approach based on the combination of
phenotypic and genotypic characteristics. However, the current situation is paradoxical in …
phenotypic and genotypic characteristics. However, the current situation is paradoxical in …
Scientific Guidance for the submission of dossiers on Food Enzymes
EFSA Panel on Food Contact Materials … - EFSA …, 2021 - Wiley Online Library
Following a request from the European Commission, EFSA developed an updated scientific
guidance to assist applicants in the preparation of applications for food enzymes. This …
guidance to assist applicants in the preparation of applications for food enzymes. This …
[HTML][HTML] Genome-Based Taxonomic Classification of the Phylum Actinobacteria
The application of phylogenetic taxonomic procedures led to improvements in the
classification of bacteria assigned to the phylum Actinobacteria but even so there remains a …
classification of bacteria assigned to the phylum Actinobacteria but even so there remains a …
A new antibiotic kills pathogens without detectable resistance
LL Ling, T Schneider, AJ Peoples, AL Spoering… - Nature, 2015 - nature.com
Antibiotic resistance is spreading faster than the introduction of new compounds into clinical
practice, causing a public health crisis. Most antibiotics were produced by screening soil …
practice, causing a public health crisis. Most antibiotics were produced by screening soil …
[HTML][HTML] Genome sequence-based species delimitation with confidence intervals and improved distance functions
Background For the last 25 years species delimitation in prokaryotes (Archaea and Bacteria)
was to a large extent based on DNA-DNA hybridization (DDH), a tedious lab procedure …
was to a large extent based on DNA-DNA hybridization (DDH), a tedious lab procedure …
VICTOR: genome-based phylogeny and classification of prokaryotic viruses
JP Meier-Kolthoff, M Göker - Bioinformatics, 2017 - academic.oup.com
Motivation Bacterial and archaeal viruses are crucial for global biogeochemical cycles and
might well be game-changing therapeutic agents in the fight against multi-resistant …
might well be game-changing therapeutic agents in the fight against multi-resistant …
Phylogenomics of Rhodobacteraceae reveals evolutionary adaptation to marine and non-marine habitats
M Simon, C Scheuner, JP Meier-Kolthoff… - The ISME …, 2017 - academic.oup.com
Abstract Marine Rhodobacteraceae (Alphaproteobacteria) are key players of
biogeochemical cycling, comprise up to 30% of bacterial communities in pelagic …
biogeochemical cycling, comprise up to 30% of bacterial communities in pelagic …
[HTML][HTML] Digital DNA-DNA hybridization for microbial species delineation by means of genome-to-genome sequence comparison
The pragmatic species concept for Bacteria and Archaea is ultimately based on DNA-DNA
hybridization (DDH). While enabling the taxonomist, in principle, to obtain an estimate of the …
hybridization (DDH). While enabling the taxonomist, in principle, to obtain an estimate of the …
[HTML][HTML] What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira
DE Fouts, MA Matthias, H Adhikarla… - PLoS neglected …, 2016 - journals.plos.org
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …
neglected and emerging zoonotic disease. While whole genome analysis of individual …