Current definitions and clinical implications of biomarkers in graft-versus-host disease

A Bidgoli, BP DePriest, MV Saatloo, H Jiang… - … and cellular therapy, 2022 - Elsevier
Hematopoietic cell transplantation (HCT) is a potentially curative treatment for many
hematologic and nonhematologic disorders. Graft-versus-host-disease (GVHD) in its acute …

Haploidentical transplants with a G-CSF/ATG-based protocol: Experience from China

ZL Xu, XJ Huang - Blood Reviews, 2023 - Elsevier
Haploidentical donor stem cell transplantation (haplo-SCT) has made great advances in
recent decades. The granulocyte colony-stimulating factor (G-CSF)-and antithymocyte …

[HTML][HTML] National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-Host disease: IV. the 2020 highly morbid forms …

D Wolff, V Radojcic, R Lafyatis, R Cinar… - … and cellular therapy, 2021 - Elsevier
Chronic graft-versus-host disease (GVHD) can be associated with significant morbidity, in
part because of nonreversible fibrosis, which impacts physical functioning (eye, skin, lung …

Association between immune-related adverse event timing and treatment outcomes

D Hsiehchen, AR Naqash, M Espinoza… - …, 2022 - Taylor & Francis
The timing of immune-related adverse events (irAE) associated with immune checkpoint
inhibitors (ICI) is highly variable. Although the development of irAE has been associated with …

Chronic graft-versus-host disease in pediatric patients: differences and challenges

E Haroun, K Agrawal, J Leibovitch, J Kassab, M Zoghbi… - Blood Reviews, 2023 - Elsevier
Despite the use of high-resolution molecular techniques for tissue typing, chronic graft-
versus-host disease (cGVHD) remains a major complication following allogeneic …

A diagnostic classifier for pediatric chronic graft-versus-host disease: results of the ABLE/PBMTC 1202 study

GDE Cuvelier, B Ng, S Abdossamadi… - Blood …, 2023 - ashpublications.org
Abstract The National Institutes of Health Consensus criteria for chronic graft-versus-host
disease (cGVHD) diagnosis can be challenging to apply in children, making pediatric …

[HTML][HTML] National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: IIb. The 2020 preemptive therapy …

J Pidala, C Kitko, SJ Lee, P Carpenter… - … and cellular therapy, 2021 - Elsevier
Chronic graft-versus-host disease (GVHD) commonly occurs after allogeneic hematopoietic
cell transplantation (HCT) despite standard prophylactic immune suppression. Intensified …

Potential novel biomarkers in chronic graft-versus-host disease

RE Crossland, F Perutelli, K Bogunia-Kubik… - Frontiers in …, 2020 - frontiersin.org
Prognostic, diagnostic or predictive biomarkers are urgently needed for assessment of
chronic graft-versus-host disease (cGvHD), a major risk for patients undergoing allogeneic …

Chronic GvHD NIH consensus project biology task force: Evolving path to personalized treatment of chronic GvHD

NP Buxbaum, G Socié, GR Hill… - Blood …, 2023 - ashpublications.org
Chronic graft-versus-host disease (cGvHD) remains a prominent barrier to allogeneic
hematopoietic stem cell transplantion as the leading cause of nonrelapse mortality and …

[HTML][HTML] Ibrutinib treatment of pediatric chronic graft-versus-host disease: primary results from the phase 1/2 iMAGINE Study

PA Carpenter, HJ Kang, KH Yoo, M Zecca… - … and cellular therapy, 2022 - Elsevier
Chronic graft-versus-host disease (cGVHD) is a potentially life-threatening complication of
allogeneic hematopoietic stem cell transplantation. Clinical data surrounding cGVHD …