Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study

S Subramaniapillai, LS Schindler, P Redmond… - Neurology, 2024 - neurology.org
Background and Objectives The aging population is growing faster than all other
demographic strata. With older age comes a greater risk of health conditions such as obesity …

Dissecting unique and common variance across body and brain health indicators using age prediction

D Beck, AMG de Lange, TP Gurholt… - Human Brain …, 2024 - Wiley Online Library
Ageing is a heterogeneous multisystem process involving different rates of decline in
physiological integrity across biological systems. The current study dissects the unique and …

Elevated blood pressure accelerates white matter brain aging among late middle-aged women: a Mendelian Randomization study in the UK Biobank

L Feng, Z Ye, C Mo, J Wang, S Liu, S Gao… - Journal of …, 2023 - journals.lww.com
Background: Elevated blood pressure (BP) is a modifiable risk factor associated with
cognitive impairment and cerebrovascular diseases. However, the causal effect of BP on …

Better Life's Essential 8 contributes to slowing the biological aging process: a cross-sectional study based on NHANES 2007–2010 data

D Wu, C Qu, P Huang, X Geng, J Zhang… - Frontiers in Public …, 2024 - frontiersin.org
Objective To investigate the relationship between Life's Essential 8 (LE8) and Phenotypic
Age Acceleration (PhenoAgeAccel) in United States adults and to explore the impact of LE8 …

Association of Cardiovascular Health With Brain Age Estimated Using Machine Learning Methods in Middle-Aged and Older Adults

H Huang, J Wang, MM Dunk, J Guo, A Dove, J Ma… - Neurology, 2024 - AAN Enterprises
Background and Objectives Cardiovascular health (CVH) has been associated with
cognitive decline and dementia, but the extent to which CVH affects brain health remains …

[PDF][PDF] Better Life's Essential 8

D Wu, C Qu, P Huang, X Geng, J Zhang, Y Shen, Z Rao… - 2024 - frontiersin.org
Objective: To investigate the relationship between Life's Essential 8 (LE8) and Phenotypic
Age Acceleration (PhenoAgeAccel) in United States adults and to explore the impact of LE8 …