The presence, role and clinical use of spermatozoal RNAs
M Jodar, S Selvaraju, E Sendler… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Spermatozoa are highly differentiated, transcriptionally inert cells
characterized by a compact nucleus with minimal cytoplasm. Nevertheless they contain a …
characterized by a compact nucleus with minimal cytoplasm. Nevertheless they contain a …
All you need to know about sperm RNAs
J Santiago, JV Silva, J Howl… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND Spermatogenesis generates a small and highly specialised type of cell that
is apparently incapable of transcription and translation. For many years, this dogma was …
is apparently incapable of transcription and translation. For many years, this dogma was …
[HTML][HTML] Single-cell RNA sequencing of human, macaque, and mouse testes uncovers conserved and divergent features of mammalian spermatogenesis
Spermatogenesis is a highly regulated process that produces sperm to transmit genetic
information to the next generation. Although extensively studied in mice, our current …
information to the next generation. Although extensively studied in mice, our current …
[HTML][HTML] MicroRNAs and spermatogenesis
N Kotaja - Fertility and sterility, 2014 - Elsevier
In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
[HTML][HTML] Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis
Spermatogenesis is a complex process in the testis and is a cornerstone of male infertility.
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …
[HTML][HTML] The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility
JR Kovac, AW Pastuszak, DJ Lamb - Fertility and sterility, 2013 - Elsevier
Although male factors account for approximately 50% of all infertility, the mechanisms
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …
Intracytoplasmic sperm injection: state of the art in humans
GD Palermo, CL O'neill, S Chow, S Cheung… - …, 2017 - rep.bioscientifica.com
Among infertile couples, 25% involve both male and female factors, while male factor alone
accounts for another 25% due to oligo-, astheno-, teratozoospermia, a combination of the …
accounts for another 25% due to oligo-, astheno-, teratozoospermia, a combination of the …
Male fertility status is associated with DNA methylation signatures in sperm and transcriptomic profiles of bovine preimplantation embryos
J Kropp, JA Carrillo, H Namous, A Daniels, SM Salih… - BMC genomics, 2017 - Springer
Background Infertility in dairy cattle is a concern where reduced fertilization rates and high
embryonic loss are contributing factors. Studies of the paternal contribution to reproductive …
embryonic loss are contributing factors. Studies of the paternal contribution to reproductive …
[HTML][HTML] Towards a multi-omics of male infertility
AO Wagner, A Turk, T Kunej - The world journal of men's health, 2023 - ncbi.nlm.nih.gov
Infertility is a common problem affecting one in six couples and in 30% of infertile couples,
the male factor is a major cause. A large number of genes are involved in spermatogenesis …
the male factor is a major cause. A large number of genes are involved in spermatogenesis …
Sperm global DNA methylation level: association with semen parameters and genome integrity
D Montjean, A Zini, C Ravel, S Belloc, A Dalleac… - …, 2015 - Wiley Online Library
Sperm DNA methylation abnormalities have been detected in oligozoospermic men.
However, the association between sperm DNA methylation defects, sperm parameters and …
However, the association between sperm DNA methylation defects, sperm parameters and …