[HTML][HTML] Adipose tissue: physiology to metabolic dysfunction

AJ Richard, U White, CM Elks, JM Stephens - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

Adipogenesis

K Sarjeant, JM Stephens - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body
insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue …

Transcriptional regulation of adipogenesis

PM de Sá, AJ Richard, H Hang… - Comprehensive …, 2011 - Wiley Online Library
Adipocytes are the defining cell type of adipose tissue. Once considered a passive
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …

What can we learn from rodents about prolactin in humans?

N Ben-Jonathan, CR LaPensee… - Endocrine …, 2008 - academic.oup.com
Abstract Prolactin (PRL) is a 23-kDa protein hormone that binds to a single-span membrane
receptor, a member of the cytokine receptor superfamily, and exerts its action via several …

STAT proteins: novel molecular targets for cancer drug discovery

J Turkson, R Jove - Oncogene, 2000 - nature.com
Abstract Signal Transducers and Activators of Transcription (STATs) are a family of
cytoplasmic proteins with roles as signal messengers and transcription factors that …

METTL3 inhibits BMSC adipogenic differentiation by targeting the JAK1/STAT5/C/EBPβ pathway via an m6A‐YTHDF2–dependent manner

Y Yao, Z Bi, R Wu, Y Zhao, Y Liu, Q Liu… - The FASEB …, 2019 - Wiley Online Library
Bone marrow stem cells (BMSCs) are multipotent stem cells that can regenerate
mesenchymal tissues, such as adipose tissue, bone, and muscle. Recent studies have …

Transcriptional factors that promote formation of white adipose tissue

UA White, JM Stephens - Molecular and cellular endocrinology, 2010 - Elsevier
Adipocytes are highly specialized cells that play a major role in energy homeostasis in
vertebrate organisms. Excess adipocyte size or number is a hallmark of obesity, which is …

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

J Turkson, T Bowman, R Garcia… - … and cellular biology, 1998 - Taylor & Francis
While signal transducers and activators of transcription (STATs) were originally discovered
as intracellular effectors of normal signaling by cytokines, increasing evidence also points to …

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

J Turkson, D Ryan, JS Kim, YI Zhang, Z Chen… - Journal of Biological …, 2001 - ASBMB
Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic
signaling proteins that participates in normal cellular responses to cytokines and growth …

[HTML][HTML] Hormonal signaling and transcriptional control of adipocyte differentiation

RF Morrison, SR Farmer - The Journal of nutrition, 2000 - Elsevier
Recent advances regarding the biology of adipose tissue have identified the adipocyte as
an important mediator in many physiologic and pathologic processes regarding energy …