The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …

Trypanosoma cruzi acute infections often go unperceived, but one third of chronically
infected individuals die of Chagas disease, showing diverse manifestations affecting the …

Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the
diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 …

Background The analytical validation of sensitive, accurate and standardized Real-Time
PCR methods for Trypanosoma cruzi quantification is crucial to provide a reliable laboratory …

Background This report describes a real-time PCR (Q-PCR) strategy to quantify
Trypanosoma cruzi (T. cruzi) DNA in peripheral blood samples from Chagas disease …

Genetic variation in Trypanosoma cruzi is likely a key determinant in transmission and
pathogenesis of Chagas disease. We have examined nine loci as markers for the extant T …

Chagas disease caused by Trypanosoma cruzi is a complex disease that is endemic and an
important problem in public health in Latin America. The T. cruzi parasite is classified into six …

Chagas' disease, caused by infection with the parasite Trypanosoma cruzi, is the major
cause of heart failure in Latin America. Classic clinical manifestations result from the …

The lack of an accurate diagnosis has been a serious obstacle to the advancement of the
anti-Trypanosoma cruzi chemotherapy and long-term infection can result in different health …

Trypanosoma cruzi is a protozoan parasite responsible for Chagas disease affecting seven
million people. The disease cycle is maintained between Triatominae insects and Mammalia …