Direct observation of the mechanical role of bacterial chaperones in protein folding
Protein folding under force is an integral source of generating mechanical energy in various
cellular processes, ranging from protein translation to degradation. Although chaperones …
cellular processes, ranging from protein translation to degradation. Although chaperones …
Mechanistic Insights into Periplasmic Chaperones as Regulators of Protein Folding and Translocation in Gram-Negative Bacteria
S Haldar, D Chaudhuri, M Bhatt - bioRxiv, 2024 - biorxiv.org
In Gram-negative bacteria, periplasmic chaperones mediate the transport and folding of
outer membrane proteins. While their substrate interaction mechanisms are well studied …
outer membrane proteins. While their substrate interaction mechanisms are well studied …
Real-time microfluidics-magnetic tweezers connects conformational stiffness with energy landscape by a single experiment
S Chakraborty, D Chaudhuri, D Chaudhuri, V Singh… - bioRxiv, 2020 - biorxiv.org
Studies of free energy, kinetics or elasticity are common to most disciplines of science.
Detailed quantification of these properties demands number of specialized technologies …
Detailed quantification of these properties demands number of specialized technologies …
The Mechanical Roles of Chaperons
Protein folding under force is an integral source of generating mechanical power to carry out
diverse cellular functions. Though chaperones interact with proteins throughout the different …
diverse cellular functions. Though chaperones interact with proteins throughout the different …