Myeloid-derived suppressor cells (MDSCs) were initially identified in humans and mice with
cancer where they profoundly suppress T cell–and NK cell–mediated antitumor immunity …

Simple Summary Small cell lung cancer (SCLC) accounts for about 15% of lung cancers
and it has limited therapeutic options and poor prognosis. There has been no real progress …

Myeloid-derived suppressor cells (MDSCs) are newly identified immature myeloid cells that
are characterized by the ability to suppress immune responses and expand during cancer …

Tumors consist of heterogeneous cell populations, and tumor heterogeneity plays key roles
in regulating tumorigenesis, metastasis, recurrence and resistance to anti-tumor therapies …

Posttransplantation cyclophosphamide (PTCy), given on days+ 3 and+ 4, reduces graft-
versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT), but …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of bone marrow
cells originating from immature myeloid cells. They exert potent immunosuppressive activity …

The immunosuppressive tumor microenvironment (TME) supports the development of
tumors and limits tumor immunotherapy, including hematological malignancies …

Myeloid-derived suppressor cells (MDSCs) can subdue inflammation. In mice with acute
graft-versus-host disease (GVHD), donor MDSC infusion enhances survival that is only …

Simple Summary Myeloid-Derived Suppressor Cells (MDSCs) have been regarded as the
main promoters of cancer development in recent years. They can protect tumor cells from …

Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes that negatively regulate the immune response to cancer and chronic infections …