p-Hydroxyphenylpyruvate dioxygenase (HPPD) is not only the useful molecular target in
treating life-threatening tyrosinemia type I, but also an important target for chemical …

4-Hydroxyphenylpyruvate dioxygenase (EC 1.13. 11.27, HPPD) is a potent new bleaching
herbicide target. Therefore, in silico structure-based virtual screening was performed in …

Breast cancer is the most common causes of death noticed in women globally. In order to
find an effective therapeutic agents our current investigation concentrating on an …

Human epidermal growth factor receptor (HER) is a family of multidomain proteins that plays
important role in the regulation of several biological functions. HER2 is a member of HER …

Glutamine synthetase (GS), which catalyzes the production of glutamine, plays essential
roles in most biological growth and biofilm formation, suggesting that GS may be used as a …

The burden of human schistosomiasis, a known but neglected tropical disease in Sub-
Saharan Africa, has been worrisome in recent years. It is becoming increasingly difficult to …

The incurable Type 2 diabetes mellitus (T2DM) has now been considered a pandemic with
only supportive care in existence. Due to the adverse effects of available anti-diabetic drugs …

Alzheimer's disease (AD) is a neurological disorder caused by the abnormal accumulation
of hyperphosphorylated proteins. Dual-specificity tyrosine phosphorylation-regulated kinase …

Background The present study investigates the potential bioactivity of twelve experimentally
designed C-2 quaternary indolinones against Providencia spp., a bacterial group of the …

Targeting ErbB family of receptors is an important therapeutic option, because of its
essential role in the broad spectrum of human cancers, including non-small cell lung cancer …