[HTML][HTML] Systemic estradiol levels with low-dose vaginal estrogens

RJ Santen, S Mirkin, B Bernick, GD Constantine - Menopause, 2020 - journals.lww.com
Objectives: To critically evaluate published systemic estradiol levels during use of low-dose
vaginal estrogens considering detection method and estrogen dose; describe challenges …

[HTML][HTML] Current strategies for quantification of estrogens in clinical research

N Denver, S Khan, NZM Homer, MR MacLean… - The Journal of steroid …, 2019 - Elsevier
Estrogens and their bioactive metabolites play key roles in regulating diverse processes in
health and disease. In particular, estrogens and estrogenic metabolites have shown both …

Colloidal gold-based immunochromatographic strip assay for the rapid detection of three natural estrogens in milk

Z Wang, L Guo, L Liu, H Kuang, C Xu - Food chemistry, 2018 - Elsevier
In this study, we developed highly sensitive and specific monoclonal antibodies (mAbs)
against estrone (E 1), 17β-estradiol (17β-E 2), and estriol (E 3). The half-maximal inhibitory …

Vanadium disulfide nanosheet boosts optical signal brightness as a superior enzyme label to improve the sensitivity of lateral flow immunoassay

Y Chen, J Ren, X Yin, Y Li, R Shu, J Wang… - Analytical …, 2022 - ACS Publications
The color-enzyme lateral flow immunoassay (LFIA) has attracted widespread attention to
expand the detection range and improve sensitivity via amplifying the color signal after …

Advancements in the gold standard: Measuring steroid sex hormones by mass spectrometry

SE Conklin, CE Knezevic - Clinical Biochemistry, 2020 - Elsevier
Sex hormones, such as testosterone and estrogens, play an essential role in regulating
physiological and reproductive development throughout the lifetime of the individual …

[HTML][HTML] Breast cancer: targeting of steroid hormones in cancerogenesis and diagnostics

M Valko-Rokytovská, P Očenáš, A Salayová… - International Journal of …, 2021 - mdpi.com
Breast cancer is the most common malignancy in women with high mortality. Sensitive and
specific methods for the detection, characterization and quantification of endogenous …

Liquid chromatography–mass spectrometry applications for quantification of endogenous sex hormones

A Gravitte, T Archibald, A Cobble… - Biomedical …, 2021 - Wiley Online Library
Liquid chromatography, coupled with tandem mass spectrometry, presents a powerful tool
for the quantification of the sex steroid hormones 17‐β estradiol, progesterone and …

[HTML][HTML] Derivatized versus non-derivatized LC-MS/MS techniques for the analysis of estrogens and estrogen-like endocrine disruptors in human plasma

J Vitku, L Horackova, L Kolatorova, M Duskova… - Ecotoxicology and …, 2023 - Elsevier
Bisphenols, parabens, alkylphenols and triclosan are anthropogenic substances with a
phenolic group that have been introduced to the environment in recent decades. As they …

[HTML][HTML] Sex hormones and genetic variants in hormone metabolic pathways associated with the risk of colorectal cancer

S Li, Y Chen, L Xie, Y Meng, L Zhu, H Chu, D Gu… - Environment …, 2020 - Elsevier
Objective The different incidence of colorectal cancer between the sexes suggests that sex
hormones may be involved in the susceptibility to colorectal cancer. The association …

[HTML][HTML] Microbiota alter metabolism and mediate neurodevelopmental toxicity of 17β-estradiol

TR Catron, A Swank, LC Wehmas, D Phelps… - Scientific Reports, 2019 - nature.com
Estrogenic chemicals are widespread environmental contaminants associated with diverse
health and ecological effects. During early vertebrate development, estrogen receptor …