One of the most replicated findings has been that hippocampus volume is decreased in
patients with major depressive disorder (MDD). Recent volumetric magnetic resonance …

Background Depression's relationship with cerebral abnormalities and cognitive decline is
temporally dynamic. Despite clear clinical utility, understanding depression's effect on …

The etiology of anorexia nervosa (AN) is still unclear, despite that it is a critical and
potentially mortal illness. A recent neurobiological model considers AN as the outcome of …

The etiology of depression is characterized by the interplay of genetic and environmental
factors and brain structural alteration. Childhood adversity is a major contributing factor in …

Rationale Chronic marijuana (MJ) use among adolescents has been associated with
structural and functional abnormalities, particularly in developing regions responsible for …

Recent models have focused on how brain-based individual differences in social sensitivity
shape affective development in adolescence, when rates of depression escalate. Given the …

Although depression is the leading cause of disability worldwide, current understanding of
the neurobiology of depression has failed to be translated into clinical practice. Major …

Background Structural brain abnormalities have been investigated in multi-genetic and
complex disorders such as major depressive disorder (MDD). Among the various candidate …

Despite consistent observations of sex differences in depression and related emotional
disorders, we do not yet know how these sex differences modulate the effects of genetic …

An evolutionary model for sex differences in disease risk posits that alleles conferring higher
risk in one sex may be protective in the other. These sexually antagonistic (SA) alleles are …