[HTML][HTML] Helminth infections: the great neglected tropical diseases

PJ Hotez, PJ Brindley, JM Bethony… - The Journal of …, 2008 - Am Soc Clin Investig
Helminths are parasitic worms. They are the most common infectious agents of humans in
developing countries and produce a global burden of disease that exceeds better-known …

[HTML][HTML] Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity

JP Hewitson, JR Grainger, RM Maizels - Molecular and biochemical …, 2009 - Elsevier
Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …

[HTML][HTML] The genome of the blood fluke Schistosoma mansoni

M Berriman, BJ Haas, PT LoVerde, RA Wilson… - Nature, 2009 - nature.com
Schistosoma mansoni is responsible for the neglected tropical disease schistosomiasis that
affects 210 million people in 76 countries. Here we present analysis of the 363 megabase …

[HTML][HTML] A research agenda for helminth diseases of humans: the problem of helminthiases

S Lustigman, RK Prichard, A Gazzinelli… - PLoS neglected …, 2012 - journals.plos.org
A disproportionate burden of helminthiases in human populations occurs in marginalised,
low-income, and resource-constrained regions of the world, with over 1 billion people in …

Current status of vaccines for schistosomiasis

DP McManus, A Loukas - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Schistosomiasis, caused by trematode blood flukes of the genus Schistosoma, is recognized
as the most important human helminth infection in terms of morbidity and mortality. Infection …

Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis

MH Tran, MS Pearson, JM Bethony, DJ Smyth… - Nature medicine, 2006 - nature.com
Schistosomes are blood-dwelling flukes that infect 200 million people worldwide and are
responsible for hundreds of thousands of deaths annually. Using a signal sequence trap, we …

The eukaryotic nucleotide excision repair pathway

RMA Costa, V Chiganças, R da Silva Galhardo… - Biochimie, 2003 - Elsevier
Nucleotide excision repair (NER) is the most versatile mechanism of DNA repair,
recognizing and dealing with a variety of helix-distorting lesions, such as the UV-induced …

[HTML][HTML] The road to elimination: current state of schistosomiasis research and progress towards the end game

P Ogongo, RK Nyakundi, GK Chege… - Frontiers in …, 2022 - frontiersin.org
The new WHO Roadmap for Neglected Tropical Diseases targets the global elimination of
schistosomiasis as a public health problem. To date, control strategies have focused on …

[图书][B] Innovation: applying knowledge in development

C Juma, L Yee-Cheong - 2005 - books.google.com
The Millennium Development Goals adopted at the UN Millennium Summit in 2000 are the
world's targets for dramatically reducing extreme poverty in its many dimensions by 2015 …

[PDF][PDF] Conquering schistosomiasis in China: the long march

J Utzinger, XN Zhou, MG Chen, R Bergquist - Acta Trop, 2005 - academia.edu
The last half-century of schistosomiasis control activities in China have brought down the
overall prevalence of human infection with Schistosoma japonicum to less than 10% of the …