Human papillomavirus molecular biology and disease association
Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …
themselves in a range of different animal species including humans. Viruses that have co …
The biology and life-cycle of human papillomaviruses
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …
[HTML][HTML] Integrated genomic and molecular characterization of cervical cancer
Cancer Genome Atlas Research Network - Nature, 2017 - ncbi.nlm.nih.gov
Cervical cancer remains one of the leading causes of cancer-related deaths worldwide.
Reported here is an extensive molecular characterization of 228 primary cervical cancers …
Reported here is an extensive molecular characterization of 228 primary cervical cancers …
[HTML][HTML] Human papillomavirus genome variants
Amongst the human papillomaviruses (HPVs), the genus Alphapapillomavirus contains HPV
types that are uniquely pathogenic. They can be classified into species and types based on …
types that are uniquely pathogenic. They can be classified into species and types based on …
Updating the natural history of human papillomavirus and anogenital cancers
AB Moscicki, M Schiffman, A Burchell, G Albero… - Vaccine, 2012 - Elsevier
This chapter addresses the natural history of anogenital human papillomavirus (HPV)
infection. Cervical infections are the best understood HPV infection. Cervical HPV …
infection. Cervical infections are the best understood HPV infection. Cervical HPV …
Human papillomavirus infection and the multistage carcinogenesis of cervical cancer
M Schiffman, N Wentzensen - Cancer epidemiology, biomarkers & …, 2013 - AACR
This short review outlines our understanding of cervical cancer precursors, concentrating on
the central etiologic role of persistent human papillomavirus infection. The stages of cervical …
the central etiologic role of persistent human papillomavirus infection. The stages of cervical …
Eurogin roadmap 2017: triage strategies for the management of HPV‐positive women in cervical screening programs
Cervical cancer screening will rely, increasingly, on HPV testing as a primary screen. The
requirement for triage tests which can delineate clinically significant infection is thus …
requirement for triage tests which can delineate clinically significant infection is thus …
[HTML][HTML] Evolution of the papillomaviridae
K Van Doorslaer - Virology, 2013 - Elsevier
Viruses belonging to the Papillomaviridae family have been isolated from a variety of
mammals, birds and non-avian reptiles. It is likely that most, if not all, amniotes carry a broad …
mammals, birds and non-avian reptiles. It is likely that most, if not all, amniotes carry a broad …
HPV16 sublineage associations with histology-specific cancer risk using HPV whole-genome sequences in 3200 women
L Mirabello, M Yeager, M Cullen… - JNCI: Journal of the …, 2016 - academic.oup.com
Background: HPV16 is a common sexually transmitted infection although few infections lead
to cervical precancer/cancer; we cannot distinguish nor mechanistically explain why only …
to cervical precancer/cancer; we cannot distinguish nor mechanistically explain why only …
[HTML][HTML] Human papillomavirus genomics: Understanding carcinogenicity
CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …