[HTML][HTML] Biomedical applications of polymers derived by reversible addition–fragmentation chain-transfer (RAFT)
BD Fairbanks, PA Gunatillake, L Meagher - Advanced drug delivery reviews, 2015 - Elsevier
RAFT-mediated polymerization, providing control over polymer length and architecture as
well as facilitating post polymerization modification of end groups, has been applied to …
well as facilitating post polymerization modification of end groups, has been applied to …
The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease
JC Evans, M Malhotra, JF Cryan… - British journal of …, 2016 - Wiley Online Library
Prostate specific membrane antigen (PSMA) otherwise known as glutamate
carboxypeptidase II (GCPII) is a membrane bound protein that is highly expressed in …
carboxypeptidase II (GCPII) is a membrane bound protein that is highly expressed in …
Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells
AV Stepanov, J Xie, Q Zhu, Z Shen, W Su… - Nature Biomedical …, 2024 - nature.com
On-target off-tumour toxicity limits the anticancer applicability of chimaeric antigen receptor
(CAR) T cells. Here we show that the tumour-targeting specificity and activity of T cells with a …
(CAR) T cells. Here we show that the tumour-targeting specificity and activity of T cells with a …
β-cyclodextrin functionalized poly (5-amidoisophthalicacid) grafted Fe3O4 magnetic nanoparticles: A novel biocompatible nanocomposite for targeted docetaxel …
Thiol-lactam initiated radical polymerization (TLIRP) was successfully employed to prepare
poly-N− 5-acrylamidoisophthalicacid grafted onto Fe 3 O 4 magnetic nanoparticles (MNPs …
poly-N− 5-acrylamidoisophthalicacid grafted onto Fe 3 O 4 magnetic nanoparticles (MNPs …
PSMA-targeted small-molecule docetaxel conjugate: Synthesis and preclinical evaluation
AE Machulkin, AA Uspenskaya, NY Zyk… - European Journal of …, 2022 - Elsevier
Prostate cancer is one of the most commonly diagnosed men's cancers and remains one of
the leading causes of cancer death. The development of approaches to the treatment of this …
the leading causes of cancer death. The development of approaches to the treatment of this …
Targeting therapy for prostate cancer by pharmaceutical and clinical pharmaceutical strategies
W Sun, Y Deng, M Zhao, Y Jiang, J Gou, Y Wang… - Journal of Controlled …, 2021 - Elsevier
For the past few years, nanotechnology has provided a lot of new treatment opportunities for
prostate cancer patients, and brilliant achievements have been acquired indeed. It not only …
prostate cancer patients, and brilliant achievements have been acquired indeed. It not only …
Design of smart HPMA copolymer-based nanomedicines
The state-of-the art in water-soluble macromolecular therapeutics has been reviewed. First
the design principles for polymer-drug conjugates are discussed followed by two recent …
the design principles for polymer-drug conjugates are discussed followed by two recent …
Magnetic Fe3O4 nanoparticles grafted with single-chain antibody (scFv) and docetaxel loaded β-cyclodextrin potential for ovarian cancer dual-targeting therapy
X Huang, C Yi, Y Fan, Y Zhang, L Zhao, Z Liang… - Materials Science and …, 2014 - Elsevier
In order to improve the therapeutic efficiency and reduce the side effects on nonpathological
cells and tissues, targeting drug delivery systems have gained more and more attraction …
cells and tissues, targeting drug delivery systems have gained more and more attraction …