The global prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …

Adipose tissue and the liver play significant roles in the regulation of whole-body energy
homeostasis, but they have not evolved to cope with the continuous, chronic, nutrient …

Turnover studies performed during progressive fasting in normal subjects indicate that the
production rate and the concentration of KB rise markedly during the early phase of fasting …

Diets that boost ketone production are increasingly used for treating several neurological
disorders. Elevation in ketones in most cases is considered favorable, as they provide …

Background Exogenous ketones make it possible to reach a state of ketosis that may
improve metabolic control in humans. Objectives The main objective of this study was to …

Objectives In non-alcoholic fatty liver disease (NAFLD), hepatic steatosis is intricately linked
with a number of metabolic alterations. We studied substrate utilisation in NAFLD during …

Background: Studies in animals show that changes in hepatic fatty acid oxidation alter liver
fat content. Human data regarding whole‐body and hepatic lipid oxidation are controversial …

Abstract Background & Aims Levels of ketone bodies have been reported to be both
increased and decreased in individuals with non‐alcoholic fatty liver disease. We …

Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic fat accumulation and
impaired insulin sensitivity. Reduced hepatic ketogenesis may promote these pathologies …

In contrast to" weightless" radioactive tracers, stable isotope tracers have nonnegligible
mass and are naturally present in the system, and the measured variable is a ratio of two …