Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management
South Asians, particularly when living in high-income countries, are at a substantially
elevated risk of type 2 diabetes compared with white Europeans, and typically develop the …
elevated risk of type 2 diabetes compared with white Europeans, and typically develop the …
Metabolic abnormalities and obesity's impact on the risk for developing preeclampsia
FT Spradley - American Journal of Physiology-Regulatory …, 2017 - journals.physiology.org
Preeclampsia (PE), a hypertensive disorder of pregnancy, is increasing as a major
contributor to perinatal and long-term morbidity of mother and offspring. PE is thought to …
contributor to perinatal and long-term morbidity of mother and offspring. PE is thought to …
Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function
Abstract Aims/hypothesis South Asians in general, and Asian Indians in particular, have
higher risk of type 2 diabetes compared with white Europeans, and a younger age of onset …
higher risk of type 2 diabetes compared with white Europeans, and a younger age of onset …
Association between hyperglycaemia and adverse perinatal outcomes in south Asian and white British women: analysis of data from the Born in Bradford cohort
D Farrar, L Fairley, G Santorelli, D Tuffnell… - The lancet Diabetes & …, 2015 - thelancet.com
Background Diagnosis of gestational diabetes predicts risk of infants who are large for
gestational age (LGA) and with high adiposity, which in turn aims to predict a future risk of …
gestational age (LGA) and with high adiposity, which in turn aims to predict a future risk of …
Risk factor screening to identify women requiring oral glucose tolerance testing to diagnose gestational diabetes: a systematic review and meta-analysis and analysis …
Background Easily identifiable risk factors including: obesity and ethnicity at high risk of
diabetes are commonly used to indicate which women should be offered the oral glucose …
diabetes are commonly used to indicate which women should be offered the oral glucose …
The identification and treatment of women with hyperglycaemia in pregnancy: an analysis of individual participant data, systematic reviews, meta-analyses and an …
D Farrar, M Simmonds, S Griffin… - Health technology …, 2016 - eprints.whiterose.ac.uk
Background Gestational diabetes mellitus (GDM) is associated with a higher risk of
important adverse outcomes. Practice varies and the best strategy for identifying and treating …
important adverse outcomes. Practice varies and the best strategy for identifying and treating …
Mendelian randomization supports causality between maternal hyperglycemia and epigenetic regulation of leptin gene in newborns
C Allard, V Desgagné, J Patenaude, M Lacroix… - Epigenetics, 2015 - Taylor & Francis
Leptin is an adipokine that acts in the central nervous system and regulates energy balance.
Animal models and human observational studies have suggested that leptin surge in the …
Animal models and human observational studies have suggested that leptin surge in the …
Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort
Background Maternal gestational diabetes (GDM) is an established risk factor for large size
at birth, but its influence on intrauterine fetal growth in different ethnic populations is less …
at birth, but its influence on intrauterine fetal growth in different ethnic populations is less …
Growing up in Bradford: protocol for the age 7–11 follow up of the Born in Bradford birth cohort
PK Bird, RRC McEachan, M Mon-Williams, N Small… - BMC public health, 2019 - Springer
Abstract Background Born in Bradford (BiB) is a prospective multi-ethnic pregnancy and
birth cohort study that was established to examine determinants of health and development …
birth cohort study that was established to examine determinants of health and development …
Differences in pregnancy metabolic profiles and their determinants between White European and South Asian women: findings from the Born in Bradford cohort
K Taylor, D L. Santos Ferreira, J West, T Yang… - Metabolites, 2019 - mdpi.com
There is widespread metabolic disruption in women upon becoming pregnant. South Asians
(SA) compared to White Europeans (WE) have more fat mass and are more insulin-resistant …
(SA) compared to White Europeans (WE) have more fat mass and are more insulin-resistant …