Assessment of sentinel lymph node status is an important step in the evaluation of patients
with melanoma for both prognosis and therapeutic management. Pathologists have an …

Highlights•Melanoma is the deadliest of skin cancers, although most cases are resectable at
diagnosis.•Use of targeted therapies and immunotherapies as adjuvant treatment …

PURPOSE Although the prognosis of patients with thin primary cutaneous melanomas
(T1,≤ 1.0 mm) is generally excellent, some develop recurrence. We sought to develop and …

Importance A neural network-based model (i31-GEP-SLNB) that uses clinicopathologic
factors (thickness, mitoses, ulceration, patient age) plus molecular analysis (31-gene …

Thick cutaneous melanomas (Breslow depth> 4 mm) are locally advanced tumors, generally
associated with poor prognosis. Nevertheless, these tumors sometimes display …

Regression in melanoma is an immunological phenomenon that results in partial or
complete replacement of the tumor with variably vascular fibrous tissue, often accompanied …

Background We evaluated the outcome of sentinel lymph node biopsies (SLNB) in patients
with thin melanoma before and after the implementation of AJCC 8th edition (AJCC8) and …

Background The relationship between collagen features (CFs) in the tumor
microenvironment and the treatment response to neoadjuvant chemoradiotherapy (nCRT) is …

Background Sentinel lymph node biopsy (SLNB) has not been studied for invasive
melanomas treated with Mohs micrographic surgery using frozen‐section MART‐1 …

Early distinction of bipolar disorder (BD) from major depressive disorder (MDD) is difficult
since no tools are available to estimate the risk of BD. In this study, we aimed to develop and …