Supramolecular hydrogelators and hydrogels: from soft matter to molecular biomaterials

X Du, J Zhou, J Shi, B Xu - Chemical reviews, 2015 - ACS Publications
In this review we intend to provide a relatively comprehensive summary of the work of
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …

Release of small bioactive molecules from physical gels

J Mayr, C Saldías, DD Díaz - Chemical Society Reviews, 2018 - pubs.rsc.org
Pharmaceutical drugs with low water solubility have always received great attention within
the scientific community. The reduced bioavailability and the need of frequent …

Supramolecular nanofibers containing arginine-glycine-aspartate (RGD) peptides boost therapeutic efficacy of extracellular vesicles in kidney repair

C Zhang, Y Shang, X Chen, AC Midgley, Z Wang… - ACS …, 2020 - ACS Publications
Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSC-EVs) have been
recognized as a promising cell-free therapy for acute kidney injury (AKI), which avoids safety …

Molecular hydrogels of therapeutic agents

F Zhao, ML Ma, B Xu - Chemical Society Reviews, 2009 - pubs.rsc.org
This tutorial review aims to introduce a new kind of biomaterials—molecular hydrogels of
therapeutic agents. Based on the molecular self-assembly in water, it is possible to transform …

Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo

Z Yang, G Liang, L Wang, B Xu - Journal of the American …, 2006 - ACS Publications
We have designed and synthesized a new hydrogelator Nap− FFGEY (1), which forms a
supramolecular hydrogel. A kinase/phosphatase switch is used to control the …

Supramolecular fluorescent hydrogelators as bio-imaging probes

N Mehwish, X Dou, Y Zhao, CL Feng - Materials Horizons, 2019 - pubs.rsc.org
Supramolecular fluorescent hydrogels (SFH) have shown great potential as detecting
probes for biomedical applications such as cell imaging, disease diagnosis, bio-sensing etc …

Supramolecular Hydrogel of a d-Amino Acid Dipeptide for Controlled Drug Release in Vivo

G Liang, Z Yang, R Zhang, L Li, Y Fan, Y Kuang… - Langmuir, 2009 - ACS Publications
A supramolecular hydrogel based on d-amino acids, which resists hydrolysis catalyzed by
proteinase K and offers long-term biostability, exhibits controlled release in vivo, as proved …

[HTML][HTML] HIF-1α overexpression in mesenchymal stem cell-derived exosome-encapsulated arginine-glycine-aspartate (RGD) hydrogels boost therapeutic efficacy of …

Q Wang, L Zhang, Z Sun, B Chi, A Zou, L Mao… - Materials Today Bio, 2021 - Elsevier
Aims Naturally secreted extracellular vesicles (EVs) play important roles in stem-mediated
cardioprotection. This study aimed to investigate the cardioprotective function and …

pH-Responsive, Bolaamphiphile-Based Smart Metallo-Hydrogels as Potential Dye-Adsorbing Agents, Water Purifier, and Vitamin B12 Carrier

S Ray, AK Das, A Banerjee - Chemistry of Materials, 2007 - ACS Publications
A protein amino acid, phenylalanine-based bolaamphiphile 1 containing a centrally located
oligomethylene group has been found to be a hydrogelator at nearly physiological pH (pH …

Using β-lactamase to trigger supramolecular hydrogelation

Z Yang, PL Ho, G Liang, KH Chow… - Journal of the …, 2007 - ACS Publications
This paper reports the rational design and synthesis of a β-lactam conjugate. Treating the
conjugate with β-lactamase cleaves the scissile β-lactam amide bond, releases a …