The scaffold protein AXIN1: gene ontology, signal network, and physiological function
L Qiu, Y Sun, H Ning, G Chen, W Zhao… - Cell Communication and …, 2024 - Springer
AXIN1, has been initially identified as a prominent antagonist within the WNT/β-catenin
signaling pathway, and subsequently unveiled its integral involvement across a diverse …
signaling pathway, and subsequently unveiled its integral involvement across a diverse …
[PDF][PDF] AMPK——运动调控骨骼肌糖脂代谢的重要激酶
沈文清, 何标, 丁树哲 - 生命科学, 2022 - lifescience.sinh.ac.cn
AMPK (5′ AMP-activated protein kinase) 是AMP 激活的, 由催化亚基α (α1/α2), 调节亚基β
(β1/β2) 和γ (γ1/γ2/γ3) 构成的异源三聚体蛋白激酶. 营养物质缺乏(无糖或低氧), 二甲双胍 …
(β1/β2) 和γ (γ1/γ2/γ3) 构成的异源三聚体蛋白激酶. 营养物质缺乏(无糖或低氧), 二甲双胍 …
[HTML][HTML] AXIN-AMPK signaling: Implications for healthy aging
The energy sensor AMP kinase (AMPK) and the master scaffolding protein, AXIN, are two
major regulators of biological processes in metazoans. AXIN-dependent regulation of AMPK …
major regulators of biological processes in metazoans. AXIN-dependent regulation of AMPK …
Hierarchical inhibition of mTORC1 by glucose starvation-triggered AXIN lysosomal translocation and by AMPK
M Li, X Wei, J Xiong, JW Feng, CS Zhang… - Life …, 2023 - academic.oup.com
When glucose is replete, mammalian/mechanistic target of rapamycin complex 1 (mTORC1)
is active and anchored to the lysosomal surface via the two GTPases, Ras-related GTPase …
is active and anchored to the lysosomal surface via the two GTPases, Ras-related GTPase …
[HTML][HTML] LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis
S Qu, Q Liao, C Yu, Y Chen, H Luo, X Xia… - Bosnian journal of …, 2022 - ncbi.nlm.nih.gov
The regenerative potential of cardiomyocytes in adult mammals is limited. The previous
studies reported that cardiomyocyte proliferation is suppressed by AMP-activated protein …
studies reported that cardiomyocyte proliferation is suppressed by AMP-activated protein …
Gene deletion of γ‐actin impairs insulin‐stimulated skeletal muscle glucose uptake in growing mice but not in mature adult mice
JR Knudsen, AB Madsen, Z Li… - Physiological …, 2022 - Wiley Online Library
The cortical cytoskeleton, consisting of the cytoplasmic actin isoforms β and/or γ‐actin, has
been implicated in insulin‐stimulated GLUT4 translocation and glucose uptake in muscle …
been implicated in insulin‐stimulated GLUT4 translocation and glucose uptake in muscle …
火把花根多糖对运动疲劳小鼠AMPK/mTOR 信号通路的影响.
杜伟, 吴思澜, 杨雪, 陈慧, 叶兰 - Tianjin Medical Journal, 2022 - search.ebscohost.com
目的研究火把花根多糖的抗运动疲劳作用及可能的作用机制. 方法24 只ICR
雄性小鼠按随机数字表法分为静止对照组, 疲劳对照组, 疲劳+ 单糖组和疲劳+ 火把花根多糖组 …
雄性小鼠按随机数字表法分为静止对照组, 疲劳对照组, 疲劳+ 单糖组和疲劳+ 火把花根多糖组 …
Lithocholic acid targets TULP3 to activate sirtuins and AMPK to retard ageing
Q Qu, Y Chen, Y Wang, S Long, W Wang, HY Yang… - bioRxiv, 2023 - biorxiv.org
Lithocholic acid (LCA), accumulated in the body during calorie restriction (CR), can confer
administered metazoans with the ability to activate AMP-activated protein kinase (AMPK) …
administered metazoans with the ability to activate AMP-activated protein kinase (AMPK) …
AXIN-AMPK signaling: Implications for healthy aging
M Avijit, BP Gupta - F1000Research, 2021 - search.proquest.com
The energy sensor AMP kinase (AMPK) and the master scaffolding protein, AXIN, are two
major regulators of biological processes in metazoans. AXIN-dependent regulation of AMPK …
major regulators of biological processes in metazoans. AXIN-dependent regulation of AMPK …