Facile assembly of modular-type phosphines for tackling modern arylation processes

MH Tse, PY Choy, FY Kwong - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus This Account presents an overview of a promising collection of phosphine
ligands simply made from the modular Fischer indolization process and their applications in …

Atropisomeric phosphine ligands bearing C–N axial chirality: applications in enantioselective Suzuki–Miyaura cross-coupling towards the assembly of tetra-ortho …

KB Gan, RL Zhong, ZW Zhang… - Journal of the American …, 2022 - ACS Publications
Biaryl phosphines bearing C (Ar)–C (Ar) axial chirality are commonly known and have been
successfully applied in many asymmetric catalyses. Nevertheless, the development of a …

Palladium‐catalyzed regioselective aromatic extension of internal alkynes through a norbornene‐controlled reaction sequence

Q Zhao, WC Fu, FY Kwong - Angewandte Chemie, 2018 - Wiley Online Library
A regioselective aromatic π‐extension reaction of internal alkynes is reported. The proposed
method employs three easily available components, namely aryl halides, 2 …

The Highly Efficient Suzuki–Miyaura Cross‐Coupling of (Hetero) aryl Chlorides and (Hetero) arylboronic Acids Catalyzed by “Bulky‐yet‐Flexible” Palladium–PEPPSI …

JS Ouyang, YF Li, FD Huang, DD Lu, FS Liu - ChemCatChem, 2018 - Wiley Online Library
A series of Pd–PEPPSI complexes were designed and synthesized. The relationship
between catalyst structure and properties was systematically investigated. It was revealed …

Upgrading Carbazolyl-Derived Phosphine Ligands Using RhI-Catalyzed PIII-Directed C–H Bond Alkylation for Catalytic CO2-Fixation Reactions

J Rzayev, Z Zhang, N Durand, JF Soulé - Organic Letters, 2022 - ACS Publications
We report an Rh (I)-catalyzed C–H bond alkylation of PhenCarPhos [N-(2-
(diphenylphosphaneyl) phenyl) carbazole] and some congener phosphine ligands with …

Ruthenium-catalyzed oxidative homocoupling of arylboronic acids in water: Ligand tuned reactivity and mechanistic study

D Tyagi, C Binnani, RK Rai, AD Dwivedi… - Inorganic …, 2016 - ACS Publications
Molecular catalysts based on water-soluble arene-Ru (II) complexes ([Ru]-1–[Ru]-5)
containing aniline (L1), 2-methylaniline (L2), 2, 6-dimethylaniline (L3), 4-methylaniline (L4) …

A General Pd-Catalyzed C2–H Arylation of Benzoxazoles with Highly Sterically Congested Aryl Chlorides Enabled by a Fittingly Tuned Ligand

W Song, MH Tse, YK Lau, CW Cheung, PY Choy… - Organic …, 2024 - ACS Publications
The benzoxazole core, featuring a sterically congested 2, 6-disubstituted aryl fragment at the
C2 position, exhibits exclusive three-dimensional structures that are essential for particular …

Palladium-Catalyzed Direct Arylation of Polyfluoroarenes for Accessing Tetra-ortho-Substituted Biaryls: Buchwald-type Ligand Having Complementary −PPh2 Moiety …

OY Yuen, MP Leung, CM So, RWY Sun… - The Journal of Organic …, 2018 - ACS Publications
The first general examples of direct C–H arylation of electron-deficient polyfluoroarenes with
challenging di-ortho-substituted aryl (heteroaryl) chlorides for tetra-ortho-substituted biaryl …

Sterically hindered amination of aryl chlorides catalyzed by a new carbazolyl-derived P, N-ligand-composed palladium complex

WI Lai, MP Leung, PY Choy, FY Kwong - Synthesis, 2019 - thieme-connect.com
A family of 2-(9H-carbazol-9-yl) phenyl-based phosphine ligands were synthesized and their
efficacy in promoting the steric hindered Buchwald–Hartwig amination was evaluated. In the …

Catalytic direct C2-alkenylation of oxazoles at parts per million levels of palladium/PhMezole-Phos complex

WC Fu, Y Wu, CM So, SM Wong, A Lei… - Organic letters, 2016 - ACS Publications
General direct C2-alkenylation of oxazoles is reported using alkenyl tosylates at parts per
million levels of palladium catalyst. From a series of ligands screened, PhMezole-Phos …