[HTML][HTML] Connective tissue growth factor induces collagen I expression in human lung fibroblasts through the Rac1/MLK3/JNK/AP-1 pathway
CH Lin, MC Yu, WH Tung, TT Chen, CC Yu… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Connective tissue growth factor (CTGF) plays an important role in lung fibrosis. In this study,
we investigated the role of Rac1, mixed-lineage kinase 3 (MLK3), c-Jun N-terminal kinase …
we investigated the role of Rac1, mixed-lineage kinase 3 (MLK3), c-Jun N-terminal kinase …
Estrogen receptor α inhibits IL-1β induction of gene expression in the mouse liver
MJ Evans, K Lai, LJ Shaw, DC Harnish… - …, 2002 - academic.oup.com
Estrogens have been suggested to modulate several inflammatory processes. Here, we
show that IL-1β treatment induced the expression of approximately 75 genes in the liver of …
show that IL-1β treatment induced the expression of approximately 75 genes in the liver of …
Peptidoglycan induces interleukin‐6 expression through the TLR2 receptor, JNK, c‐Jun, and AP‐1 pathways in microglia
We recently reported that peptidoglycan (PGN), a cell wall component of the Gram‐positive
bacterium, induces NF‐κB activation and microglia activation. However, PGN‐regulated AP …
bacterium, induces NF‐κB activation and microglia activation. However, PGN‐regulated AP …
[HTML][HTML] Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction
DM Silverstein, BR Travis, BA Thornhill, JS Schurr… - Kidney international, 2003 - Elsevier
Altered expression of immune modulator and structural genes in neonatal unilateral ureteral
obstruction. Background Congenital obstructive nephropathy is a condition characterized by …
obstruction. Background Congenital obstructive nephropathy is a condition characterized by …
[HTML][HTML] Interferon-γ stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2: A Potentially novel …
JR Mead, TR Hughes, SA Irvine, NN Singh… - Journal of Biological …, 2003 - ASBMB
Interferon-γ (IFN-γ) is a pleiotropic cytokine that modulates the immune function, cell
proliferation, apoptosis, macrophage activation, and numerous other cellular responses …
proliferation, apoptosis, macrophage activation, and numerous other cellular responses …
[HTML][HTML] A novel role of Sp1 and Sp3 in the interferon-γ-mediated suppression of macrophage lipoprotein lipase gene transcription
TR Hughes, TS Tengku-Muhammad, SA Irvine… - Journal of Biological …, 2002 - ASBMB
The regulation of macrophage lipoprotein lipase by cytokines is of potentially crucial
importance in the pathogenesis of atherosclerosis. We have shown previously that …
importance in the pathogenesis of atherosclerosis. We have shown previously that …
Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway
CC Yu, MJ Hsu, ML Kuo, RFC Chen… - The Journal of …, 2009 - journals.aai.org
Thrombin plays an important role in lung inflammatory diseases. Thrombin can induce
connective tissue growth factor (CTGF) expression in lung fibroblasts. However, little is …
connective tissue growth factor (CTGF) expression in lung fibroblasts. However, little is …
Comparative transcriptomics highlights the role of the activator protein 1 transcription factor in the host response to ebolavirus
JW Wynne, S Todd, V Boyd, M Tachedjian… - Journal of …, 2017 - Am Soc Microbiol
Ebolavirus and Marburgvirus comprise two genera of negative-sense single-stranded RNA
viruses that cause severe hemorrhagic fevers in humans. Despite considerable research …
viruses that cause severe hemorrhagic fevers in humans. Despite considerable research …
Potentiation of lipopolysaccharide-inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun N-terminal kinase-mediated activation of CCAAT/enhancer …
YH Cho, CH Lee, SG Kim - Molecular Pharmacology, 2003 - ASPET
Ceramide, formed by sphingomyelinase, is involved in the expression of cyclooxygenase-2
(COX-2). This study examines the effect of C2-ceramide (C2), a cell-permeable ceramide …
(COX-2). This study examines the effect of C2-ceramide (C2), a cell-permeable ceramide …
Induction of human matrix metalloproteinase-12 gene transcriptional activity by GM-CSF requires the AP-1 binding site in human U937 monocytic cells
L Wu, A Tanimoto, Y Murata, J Fan, Y Sasaguri… - Biochemical and …, 2001 - Elsevier
Matrix metalloproteinase-12 (MMP-12) is critical for the migration of monocytes/
macrophages into inflammatory sites through the basement membranes. We previously …
macrophages into inflammatory sites through the basement membranes. We previously …