Crohn's disease

G Roda, S Chien Ng, PG Kotze, M Argollo… - Nature Reviews …, 2020 - nature.com
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Inclusion of the mesentery in ileocolic resection for Crohn's disease is associated with reduced surgical recurrence

CJ Coffey, MG Kiernan, SM Sahebally… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Inclusion of the mesentery during resection for colorectal
cancer is associated with improved outcomes but has yet to be evaluated in Crohn's …

Management of Crohn's disease in adults

GR Lichtenstein, SB Hanauer… - Official journal of the …, 2009 - journals.lww.com
Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

Beyond neurotransmission: acetylcholine in immunity and inflammation

MA Cox, C Bassi, ME Saunders… - Journal of internal …, 2020 - Wiley Online Library
Acetylcholine (ACh) is best known as a neurotransmitter and was the first such molecule
identified. ACh signalling in the neuronal cholinergic system has long been known to …

The vagal innervation of the gut and immune homeostasis

G Matteoli, GE Boeckxstaens - Gut, 2013 - gut.bmj.com
The central nervous system interacts dynamically with the immune system to modulate
inflammation through humoral and neural pathways. Recently, in animal models of sepsis …

Systematic review with meta‐analysis: the adverse effects of tobacco smoking on the natural history of Crohn's disease

N To, DJ Gracie, AC Ford - Alimentary pharmacology & …, 2016 - Wiley Online Library
Background Tobacco smoking is a well‐established risk factor for the development of
Crohn's disease, and this may lead to a more complicated disease course. However, recent …

The effect of smoking after surgery for Crohn's disease: a meta-analysis of observational studies

GE Reese, T Nanidis, C Borysiewicz… - International journal of …, 2008 - Springer
Objective The aim of the study was to quantify the risk of disease recurrence associated with
cigarette smoking for individuals with Crohn's disease after disease-modifying surgery …

Safety and Efficacy of Strictureplasty for Crohn's Disease: A Systematic Review and Meta-Analysis: W. Donald Buie, MD: Editor

T Yamamoto, VW Fazio, PP Tekkis - Diseases of the colon & …, 2007 - journals.lww.com
Purpose: This study was designed to review safety and efficacy of strictureplasty for Crohn's
disease. Methods: A literature search was performed to identify studies published between …

Interventions for prevention of post‐operative recurrence of Crohn's disease

G Doherty, G Bennett, S Patil… - Cochrane Database …, 2009 - cochranelibrary.com
Background Recurrence of Crohn's disease is common after intestinal resection. A number
of agents have been studied in controlled trials with the goal of reducing the risk of …