Perspectives on the technological aspects and biomedical applications of virus‐like particles/nanoparticles in reproductive biology: insights on the medicinal and …

V Chandrasekar, AV Singh… - Advanced …, 2022 - Wiley Online Library
Increasing data on the infection indicate that maternal infections are severe. Under the
realms of vaccine development, virus‐like particles (VLP)/nanoparticles (NPs) hold the …

The role of extracellular matrix in normal and pathological pregnancy: Future applications of microphysiological systems in reproductive medicine

BB O'Connor, BD Pope, MM Peters… - Experimental …, 2020 - journals.sagepub.com
Remodeling of extracellular matrix in the womb facilitates the dramatic morphogenesis of
maternal and placental tissues necessary to support fetal development. In addition to …

The L-NAME mouse model of preeclampsia and impact to long-term maternal cardiovascular health

N de Alwis, NK Binder, S Beard… - Life science …, 2022 - life-science-alliance.org
Preeclampsia affects∼ 2–8% of pregnancies worldwide. It is associated with increased long-
term maternal cardiovascular disease risk. This study assesses the effect of the …

LncRNA MALAT1 regulates trophoblast cells migration and invasion via miR-206/IGF-1 axis

HY Wu, XH Wang, K Liu, JL Zhang - Cell Cycle, 2020 - Taylor & Francis
Preeclampsia (PE) is a pregnancy-specific syndrome that substantially leads to maternal
and fetal mortality. Multiple factors contribute to the disease, but the exact pathogenesis still …

Acute kidney injury in pregnancy: the need for higher awareness. A pragmatic review focused on what could be improved in the prevention and care of pregnancy …

GB Piccoli, E Zakharova, R Attini… - Journal of clinical …, 2018 - mdpi.com
Pregnancy-related acute kidney injury (pAKI), preeclampsia (PE), and the hypertensive
disorders of pregnancy are closely related conditions, which are, in turn, frequently linked to …

Maternal serum uric acid, creatinine and blood urea levels in the prediction of pre-eclampsia among pregnant women attending ANC and delivery services at Bahir …

E Tesfa, A Munshea, E Nibret, D Mekonnen… - Heliyon, 2022 - cell.com
Background Pre-eclampsia (PE) is a metabolic disorder that adversely affects the lives of
mother and their infants. Even though, several studies have been conducted on PE, no …

Analysis of circulating microRNA signatures and preeclampsia development

ML Martinez-Fierro, I Garza-Veloz - Cells, 2021 - mdpi.com
microRNAs are important regulators of cell processes and have been proposed as potential
preeclampsia biomarkers. We evaluated serum microRNA expression profiling to identify …

The diagnosis values of serum STAT4 and sEng in preeclampsia

L Zhang, X Li, C Zhou, Z You, J Zhang… - Journal of Clinical …, 2020 - Wiley Online Library
Objective To detect the levels of signal transducer and activator of transcription 4 (STAT4)
and soluble endoglin (sEng) in preeclampsia patients and analyze the diagnostic values of …

Fibroblast growth factor type 2 (FGF2) administration attenuated the clinical manifestations of preeclampsia in a murine model induced by L-NAME

ML Martinez-Fierro, GP Hernadez-Delgadillo… - Frontiers in …, 2021 - frontiersin.org
Background: In preeclampsia, a hypertensive disorder of pregnancy, the poor remodeling of
spiral arteries leads to placental hypoperfusion and ischemia, provoking generalized …

Cord blood DNA methylation signatures associated with preeclampsia are enriched for cardiovascular pathways: insights from the VDAART trial

HM Knihtilä, P Kachroo, I Shadid, A Raissadati… - Ebiomedicine, 2023 - thelancet.com
Background Preeclampsia has been associated with maternal epigenetic changes, in
particular DNA methylation changes in the placenta. It has been suggested that …