Histone modifications in embryo implantation and placentation: insights from mouse models

S Bi, Z Tu, D Chen, S Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Embryo implantation and placentation play pivotal roles in pregnancy by facilitating crucial
maternal-fetal interactions. These dynamic processes involve significant alterations in gene …

Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss

VK Sirohi, TI Medrano, A Kannan, IC Bagchi, PS Cooke - Iscience, 2023 - cell.com
Maternal uterine remodeling facilitates embryo implantation, stromal cell decidualization and
placentation, and perturbation of these processes may cause pregnancy loss. Enhancer of …

Spatial and molecular anatomy of the endometrium during embryo implantation: a current overview of key regulators of blastocyst invasion

S Akaeda, S Aikawa, Y Hirota - The FEBS Journal, 2024 - Wiley Online Library
Embryo implantation is composed of three steps: blastocyst apposition, adhesion/attachment
and invasion. Blastocyst invasion has been studied less extensively than the other two …

The histone methyltransferase KMT2D is essential for embryo implantation via regulating precise differentiation of endometrial cells

R Kobayashi, Y Tajika, J Kohmaru, S Morita… - Cell Death …, 2024 - nature.com
Embryo implantation failures are a major challenge in reproductive medicine, but the
underlying mechanism remains poorly understood. Successful implantation requires …

Effect of estradiol after bacterial infection on the Wnt/β-catenin pathway in bovine endometrium epithelial cells and organoids

Y Zhang, Y Zhuang, J Zhou, X Xie, M Sun, M Zheng… - Theriogenology, 2024 - Elsevier
Endometritis is a disease caused by a postpartum bacterial infection with a poor prognosis
that primarily affects dairy cows. Three-dimensional organoids have been used as a model …