mRNA vaccines against SARS-CoV-2: Advantages and caveats
M Echaide, L Chocarro de Erauso… - International Journal of …, 2023 - mdpi.com
The application of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2 infection has
constituted a determinant resource to control the COVID-19 pandemic. Since the beginning …
constituted a determinant resource to control the COVID-19 pandemic. Since the beginning …
Predictive biomarkers for checkpoint inhibitor immune-related adverse events
I Les, M Martinez, I Perez-Francisco, M Cabero… - Cancers, 2023 - mdpi.com
Simple Summary Immune-checkpoint inhibitors (ICIs) are increasingly used in the treatment
of cancer, but they cause immune-related adverse events (irAEs) in around 40% of patients …
of cancer, but they cause immune-related adverse events (irAEs) in around 40% of patients …
Plasma fractalkine contributes to systemic myeloid diversity and PD‐L1/PD‐1 blockade in lung cancer
A Bocanegra, G Fernández‐Hinojal, D Ajona… - EMBO …, 2023 - embopress.org
Recent studies highlight the importance of baseline functional immunity for immune
checkpoint blockade therapies. High‐dimensional systemic immune profiling is performed in …
checkpoint blockade therapies. High‐dimensional systemic immune profiling is performed in …
Overcoming anti-PD-1/PD-L1 immune checkpoint blockade resistance: the role of macrophage, neutrophils and mast cells in the tumor microenvironment
LB Kwantwi - Clinical and Experimental Medicine, 2023 - Springer
In recent years, the anti-PD-1/PD-L1 blockade has become a game changer in cancer
treatment following the unprecedented response rate. Regardless of the substantial therapy …
treatment following the unprecedented response rate. Regardless of the substantial therapy …
Leading edge: intratumor delivery of monoclonal antibodies for the treatment of solid tumors
E Blanco, L Chocarro, L Fernández-Rubio… - International Journal of …, 2023 - mdpi.com
Immunotherapies based on immune checkpoint blockade have shown remarkable clinical
outcomes and durable responses in patients with many tumor types. Nevertheless, these …
outcomes and durable responses in patients with many tumor types. Nevertheless, these …
[PDF][PDF] Chocarro de Erauso
M Echaide - Bocanegra, A., Blanco, E., Kochan, G. and …, 2023 - academica-e.unavarra.es
The application of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2 infection has
constituted a determinant resource to control the COVID-19 pandemic. Since the beginning …
constituted a determinant resource to control the COVID-19 pandemic. Since the beginning …
Immune profiling uncovers memory T-cell responses with a Th17 signature in cancer patients with previous SARS-CoV-2 infection followed by mRNA vaccination
M Echaide, I Labiano, M Delgado… - Cancers, 2022 - mdpi.com
Simple Summary Cancer patients are considered a high-risk group for infectious diseases
including COVID-19. The protective effects of vaccination are unclear in oncologic patients …
including COVID-19. The protective effects of vaccination are unclear in oncologic patients …
[HTML][HTML] Fractalkine in health and disease
C Rodriguez, L Chocarro, M Echaide, K Ausin… - International Journal of …, 2024 - mdpi.com
CX3CL1 is one of the 50 up-to-date identified and characterized chemokines. While other
chemokines are produced as small, secreted proteins, CX3CL1 (fractalkine) is synthetized …
chemokines are produced as small, secreted proteins, CX3CL1 (fractalkine) is synthetized …
Potent clinical predictive and systemic adjuvant therapeutic value of plasma fractalkine in PD-L1/PD-1 blockade immunotherapy for lung cancer
A Bocanegra, G Fernández, D Ajona, H Arasanz… - MedRxiv, 2022 - medrxiv.org
Recent studies highlight the importance of baseline functional immunity for efficacious
immune checkpoint blockade therapies. High-dimensional systemic immune profiling was …
immune checkpoint blockade therapies. High-dimensional systemic immune profiling was …
Targeting tumor-associated macrophage: an adjuvant strategy for lung cancer therapy
L Liu, G Chen, S Gong, R Huang, C Fan - Frontiers in immunology, 2023 - frontiersin.org
The emergence of immunotherapy has revolutionized the treatment landscape for various
types of cancer. Nevertheless, lung cancer remains one of the leading causes of cancer …
types of cancer. Nevertheless, lung cancer remains one of the leading causes of cancer …