Tumor angiogenesis: causes, consequences, challenges and opportunities

R Lugano, M Ramachandran, A Dimberg - Cellular and Molecular Life …, 2020 - Springer
Tumor vascularization occurs through several distinct biological processes, which not only
vary between tumor type and anatomic location, but also occur simultaneously within the …

Oxidative stress and cellular response to doxorubicin: a common factor in the complex milieu of anthracycline cardiotoxicity

D Cappetta, A De Angelis, L Sapio… - Oxidative medicine …, 2017 - Wiley Online Library
The production of reactive species is a core of the redox cycling profile of anthracyclines.
However, these molecular characteristics can be viewed as a double‐edged sword acting …

Unraveling the role of angiogenesis in cancer ecosystems

I Zuazo-Gaztelu, O Casanovas - Frontiers in Oncology, 2018 - frontiersin.org
Activation of the tumor and stromal cell-driven angiogenic program is one of the first
requirements in the tumor ecosystem for growth and dissemination. The understanding of …

[HTML][HTML] Age-related impairment of vascular structure and functions

X Xu, B Wang, C Ren, J Hu, DA Greenberg… - Aging and …, 2017 - ncbi.nlm.nih.gov
Among age-related diseases, cardiovascular and cerebrovascular diseases are major
causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age …

Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?

EE Creemers, AJ Tijsen, YM Pinto - Circulation research, 2012 - Am Heart Assoc
In the past few years, the crucial role of different micro-RNAs (miRNAs) in the cardiovascular
system has been widely recognized. Recently, it was discovered that extracellular miRNAs …

Angiogenesis and inflammation crosstalk in diabetic retinopathy

M Capitão, R Soares - Journal of cellular biochemistry, 2016 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most prevalent microvascular complications of
diabetes and one of the most frequent causes of blindness in active age. Etiopathogenesis …

Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing

GK Kolluru, SC Bir, CG Kevil - International journal of vascular …, 2012 - Wiley Online Library
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by inappropriate
hyperglycemia due to lack of or resistance to insulin. Patients with DM are frequently afflicted …

Current and emerging biomarkers of frailty in the elderly

AA Saedi, J Feehan, S Phu, G Duque - Clinical interventions in …, 2019 - Taylor & Francis
The term “frailty” is used to describe a subset of older adults who appear weaker and more
vulnerable than their age-matched counterparts, despite having similar comorbidities …

Vascular smooth muscle cells in intimal hyperplasia, an update

S Déglise, C Bechelli, F Allagnat - Frontiers in physiology, 2023 - frontiersin.org
Arterial occlusive disease is the leading cause of death in Western countries. Core
contemporary therapies for this disease include angioplasties, stents, endarterectomies and …

Fundamentals and application of magnetic particles in cell isolation and enrichment: a review

BD Plouffe, SK Murthy, LH Lewis - Reports on Progress in …, 2014 - iopscience.iop.org
Magnetic sorting using magnetic beads has become a routine methodology for the
separation of key cell populations from biological suspensions. Due to the inherent ability of …