[HTML][HTML] Alzheimer's disease pathophysiology in the retina
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
The use of optical coherence tomography in neurology: a review
JS Xie, L Donaldson, E Margolin - Brain, 2022 - academic.oup.com
Optical coherence tomography is a non-invasive, cost-efficient technique that provides high-
resolution in vivo imaging of retinal tissue. The peripapillary retinal nerve fibre layer and …
resolution in vivo imaging of retinal tissue. The peripapillary retinal nerve fibre layer and …
Retinal pathological features and proteome signatures of Alzheimer's disease
Alzheimer's disease (AD) pathologies were discovered in the accessible neurosensory
retina. However, their exact nature and topographical distribution, particularly in the early …
retina. However, their exact nature and topographical distribution, particularly in the early …
The gut microbiota in retinal diseases
The gut microbiota is a complex ecosystem that inhabits the gastrointestinal tract and
consists of archaea, fungi, viruses, and bacteria, with bacteria being dominant. From birth …
consists of archaea, fungi, viruses, and bacteria, with bacteria being dominant. From birth …
Association between retinal layer thickness and cognitive decline in older adults
Importance Retinal layer thickness is hypothesized to be related to cognitive function in
patients with mild cognitive impairment (MCI) and Alzheimer disease (AD). However …
patients with mild cognitive impairment (MCI) and Alzheimer disease (AD). However …
[HTML][HTML] The retina: A window in which to view the pathogenesis of Alzheimer's disease
J Zhang, L Shi, Y Shen - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most familiar type of dementia affecting elderly populations
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …
Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions
J Alber, F Bouwman, J den Haan… - Alzheimer's & …, 2024 - Wiley Online Library
There is emerging evidence that amyloid beta protein (Aβ) and tau‐related lesions in the
retina are associated with Alzheimer's disease (AD). Aβ and hyperphosphorylated (p)‐tau …
retina are associated with Alzheimer's disease (AD). Aβ and hyperphosphorylated (p)‐tau …
OCT Imaging in Murine Models of Alzheimer's Disease in a Systematic Review: Findings, Methodology and Future Perspectives
The murine models of Alzheimer's disease (AD) have advanced our understanding of the
pathophysiology. In vivo studies of the retina using optical coherence tomography (OCT) …
pathophysiology. In vivo studies of the retina using optical coherence tomography (OCT) …
Salivary exosomes in health and disease: future prospects in the eye
A Liu, B Hefley, P Escandon, SE Nicholas… - International journal of …, 2023 - mdpi.com
Exosomes are a group of vesicles that package and transport DNA, RNA, proteins, and
lipids to recipient cells. They can be derived from blood, saliva, urine, and/or other biological …
lipids to recipient cells. They can be derived from blood, saliva, urine, and/or other biological …
Retinal imaging biomarkers of Alzheimer's disease: A systematic review and meta‐analysis of studies using brain amyloid beta status for case definition
G Ashraf, M McGuinness, MA Khan… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction We performed a systematic review and meta‐analysis of the association
between retinal imaging parameters and Alzheimer's disease (AD). Methods PubMed …
between retinal imaging parameters and Alzheimer's disease (AD). Methods PubMed …