[HTML][HTML] Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the
COVID-19 pandemic, it has become one of the most therapeutically targeted human …
COVID-19 pandemic, it has become one of the most therapeutically targeted human …
[HTML][HTML] The ACE2/angiotensin-(1–7)/MAS axis of the renin-angiotensin system: focus on angiotensin-(1–7)
RAS Santos, WO Sampaio, AC Alzamora… - Physiological …, 2017 - journals.physiology.org
The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …
system and hydroelectrolyte balance, with an influence on organs and functions throughout …
Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
X Zou, K Chen, J Zou, P Han, J Hao, Z Han - Frontiers of medicine, 2020 - Springer
It has been known that, the novel coronavirus, 2019-nCoV, which is considered similar to
SARS-CoV, invades human cells via the receptor angiotensin converting enzyme II (ACE2) …
SARS-CoV, invades human cells via the receptor angiotensin converting enzyme II (ACE2) …
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
R Yan, Y Zhang, Y Li, L Xia, Y Guo, Q Zhou - Science, 2020 - science.org
Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for severe acute respiratory
syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing …
syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing …
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection
Abstract Angiotensin-converting enzyme 2 (ACE2) is the main entry point in airway epithelial
cells for SARS-CoV-2. ACE2 binding to the SARS-CoV-2 protein spike triggers viral fusion …
cells for SARS-CoV-2. ACE2 binding to the SARS-CoV-2 protein spike triggers viral fusion …
D‐Dimer and prothrombin time are the significant indicators of severe COVID‐19 and poor prognosis
H Long, L Nie, X Xiang, H Li, X Zhang… - BioMed research …, 2020 - Wiley Online Library
Objective. To investigate the value of coagulation indicators D‐dimer (DD), prothrombin time
(PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (Fg) in …
(PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (Fg) in …
Alterations in microbiota of patients with COVID-19: potential mechanisms and therapeutic interventions
The global coronavirus disease 2019 (COVID-19) pandemic is currently ongoing. It is
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A high …
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A high …
ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities–role of gut microbiota dysbiosis
Abstract Coronavirus disease 19 (COVID-19) is a pandemic condition caused by the new
coronavirus SARS-CoV-2. The typical symptoms are fever, cough, shortness of breath …
coronavirus SARS-CoV-2. The typical symptoms are fever, cough, shortness of breath …
[HTML][HTML] Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy
Y Jiang, L Rubin, T Peng, L Liu, X Xing… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
The COVID-19 outbreak is emerging as a significant public health challenge. Excessive
production of proinflammatory cytokines, also known as cytokine storm, is a severe clinical …
production of proinflammatory cytokines, also known as cytokine storm, is a severe clinical …
Amino acid homeostasis and signalling in mammalian cells and organisms
S Bröer, A Bröer - Biochemical Journal, 2017 - portlandpress.com
Cells have a constant turnover of proteins that recycle most amino acids over time. Net loss
is mainly due to amino acid oxidation. Homeostasis is achieved through exchange of …
is mainly due to amino acid oxidation. Homeostasis is achieved through exchange of …