Antimicrobial peptides: key components of the innate immune system

M Pasupuleti, A Schmidtchen… - Critical reviews in …, 2012 - Taylor & Francis
Life-threatening infectious diseases are on their way to cause a worldwide crisis, as treating
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …

The porcine innate immune system: an update

KH Mair, C Sedlak, T Käser, A Pasternak… - Developmental & …, 2014 - Elsevier
Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …

Potential of immunomodulatory host defense peptides as novel anti-infectives

DM Easton, A Nijnik, ML Mayer, REW Hancock - Trends in biotechnology, 2009 - cell.com
A fundamentally new strategy for the treatment of infectious disease is the modulation of host
immune responses to enhance clearance of infectious agents and reduce tissue damage …

Polymeric nanoparticle-based vaccine adjuvants and delivery vehicles

EA Grego, AC Siddoway, M Uz, L Liu… - … for Rational Vaccine …, 2020 - Springer
As vaccine formulations have progressed from including live or attenuated strains of
pathogenic components for enhanced safety, developing new adjuvants to more effectively …

[HTML][HTML] Pathophysiology of environmental enteric dysfunction and its impact on oral vaccine efficacy

C Marie, A Ali, K Chandwe, WA Petri Jr, P Kelly - Mucosal immunology, 2018 - Elsevier
Environmental enteric dysfunction (EED) refers to a subclinical disorder of intestinal function
common in tropical countries and in settings of poverty and economic disadvantage. The …

A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity

J Kindrachuk, H Jenssen, M Elliott, R Townsend… - Vaccine, 2009 - Elsevier
There has been an increased demand for the development of novel vaccine adjuvants that
lead to enhanced induction of protection from infectious challenges and development of …

Bath immunostimulation of rainbow trout (Oncorhynchus mykiss) fry induces enhancement of inflammatory cytokine transcripts, while repeated bath induce no …

Z Zhang, T Swain, J Bøgwald, RA Dalmo… - Fish & shellfish …, 2009 - Elsevier
The application of immunostimulants may be a cost-effective practice in production of
delicate and fragile fish fry since it may confer disease resistance. Bath administration to fish …

[HTML][HTML] Vaccines in veterinary medicine: a brief review of history and technology

S McVey, J Shi - The Veterinary clinics of North America. Small …, 2010 - ncbi.nlm.nih.gov
The use of vaccines in veterinary medicine has progressed from an experimental adventure
to a routine and relatively safe practice. The common and aggressive use of efficacious …

Development and characterization of novel carrier gel core liposomes based transmission blocking malaria vaccine

S Tiwari, AK Goyal, N Mishra, K Khatri, B Vaidya… - Journal of controlled …, 2009 - Elsevier
The aim of present work was to investigate the potential utility of novel carrier gel core
liposomes for intramuscular delivery of transmission blocking malaria antigen Pfs25 and to …

Novel vaccine formulations against pertussis offer earlier onset of immunity and provide protection in the presence of maternal antibodies

M Polewicz, A Gracia, S Garlapati, J Van Kessel… - Vaccine, 2013 - Elsevier
Whooping cough is a respiratory illness most severe in infants and young children. While the
introduction of whole-cell (wP) and acellular pertussis (aP) vaccines has greatly reduced the …