Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

JS Zifodya, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …

Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults

KR Steingart, I Schiller, DJ Horne, M Pai… - Cochrane database …, 2014 - cochranelibrary.com
Background Accurate, rapid detection of tuberculosis (TB) and TB drug resistance is critical
for improving patient care and decreasing TB transmission. Xpert® MTB/RIF assay is an …

[HTML][HTML] Multidrug-resistant tuberculosis and culture conversion with bedaquiline

AH Diacon, A Pym, MP Grobusch… - … England Journal of …, 2014 - Mass Medical Soc
Background Bedaquiline (Sirturo, TMC207), a diarylquinoline that inhibits mycobacterial
ATP synthase, has been associated with accelerated sputum-culture conversion in patients …

The WHO 2014 global tuberculosis report—further to go

A Zumla, A George, V Sharma, RHN Herbert… - The Lancet Global …, 2015 - thelancet.com
In May 2014, the World Health Assembly officially approved the Draft Global Strategy and
Targets for Tuberculosis Prevention, Care and Control after 2015. 1 The target of the …

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance

H Zhang, D Li, L Zhao, J Fleming, N Lin, T Wang… - Nature …, 2013 - nature.com
The worldwide emergence of multidrug-resistant (MDR) and extensively drug-resistant
(XDR) tuberculosis threatens to make this disease incurable,. Drug resistance mechanisms …

Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts

BJ Marais, K Lönnroth, SD Lawn… - The Lancet infectious …, 2013 - thelancet.com
Recent data for the global burden of disease reflect major demographic and lifestyle
changes, leading to a rise in non-communicable diseases. Most countries with high levels of …

Scaling up interventions to achieve global tuberculosis control: progress and new developments

M Raviglione, B Marais, K Floyd, K Lönnroth… - The Lancet, 2012 - thelancet.com
Tuberculosis is still one of the most important causes of death worldwide. The 2010 Lancet
tuberculosis series provided a comprehensive overview of global control efforts and …

Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an …

SM Graham, T Ahmed, F Amanullah… - Journal of Infectious …, 2012 - academic.oup.com
There is a critical need for improved diagnosis of tuberculosis in children, particularly in
young children with intrathoracic disease as this represents the most common type of …

Balancing water sustainability and public health goals in the face of growing concerns about antibiotic resistance

A Pruden - 2014 - ACS Publications
Global initiatives are underway to advance the sustainability of urban water infrastructure
through measures such as water reuse. However, there are growing concerns that …

Tuberculosis treatment and management—an update on treatment regimens, trials, new drugs, and adjunct therapies

A Zumla, J Chakaya, R Centis, L D'Ambrosio… - The Lancet …, 2015 - thelancet.com
WHO estimates that 9 million people developed active tuberculosis in 2013 and 1· 5 million
people died from it. Multidrug-resistant (MDR) and extensively drug-resistant (XDR) …