Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

Alterations in brain intrinsic activity—as organized in resting-state networks (RSNs) such as
sensorimotor network (SMN), salience network (SN), and default-mode network (DMN) …

Background: Lysergic acid diethylamide (LSD) has agonist activity at various serotonin (5-
HT) and dopamine receptors. Despite the therapeutic and scientific interest in LSD, specific …

Lysergic acid diethylamide (LSD) is a non-selective serotonin-receptor agonist that was first
synthesized in 1938 and identified as (potently) psychoactive in 1943. Psychedelics have …

A core aspect of the human self is the attribution of personal relevance to everyday stimuli
enabling us to experience our environment as meaningful [1]. However, abnormalities in the …

There has been increasing interest in using neuroimaging measures to predict psychiatric
disorders. However, predictions usually rely on large brain networks and large disorder …

Psychedelics are undergoing a major resurgence of scientific and clinical interest. While
multiple theories and frameworks have been proposed, there is yet no universal agreement …

Neuroimaging studies of psychedelics have advanced our understanding of hierarchical
brain organization and the mechanisms underlying their subjective and therapeutic effects …

This review examines the role of trauma in psychiatric morbidity and analogous
psychoneurobiological changes. Trauma is a necessary criterion for Post-Traumatic Stress …

The success of serotonin-selective reuptake inhibitors has lent support to the monoamine
theory of major depressive disorder (MDD). This issue has been addressed in a number of …