Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack
antigen specificity and be devoid of immunological memory. Strategies that can induce …

Invasive fungal pathogens are major causes of human mortality and morbidity,. Although
numerous secreted effector proteins that reprogram innate immunity to promote virulence …

The fertility of women declines sharply after age 35 and is essentially lost upon menopause
at age 51. The ovary plays an important part in aging-associated changes in women's …

Cryptococcosis, caused by Cryptococcus neoformans, has been demonstrated to be
controlled by T helper (Th) 1 cells while Th2 cells are associated with fungal growth and …

Macrophages are key cells in the innate immune system. They phagocytose pathogens and
cellular debris, promote inflammation, and have important roles in tumor immunity …

Invasive fungal infections pose a major threat to human health. Bacterial and protozoan
pathogens secrete protein effectors that overcome innate immune barriers to promote …

Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …

Classic cell wall components of fungi comprise the polysaccharides glucans and chitin, in
association with glycoproteins and pigments. During the last decade, however, system …